Expert Q&A

Would I have any potential stretch marks if I went from 225 to 175 — how a functional medicine approach differs

Understanding Stretch Marks During 50-Pound Weight Loss

Losing 50 pounds from 225 to 175 is a meaningful goal that can dramatically improve blood pressure, blood sugar control, and joint comfort. However, many in their mid-40s to mid-50s wonder about potential stretch marks. These occur when skin stretches rapidly and collagen fibers tear, often during quick fat gain or loss. At this weight range, the risk is moderate—especially if the weight was carried around the abdomen where skin has already stretched. Women experiencing perimenopausal hormonal shifts face higher odds because declining estrogen reduces skin elasticity by up to 30%.

In my functional medicine practice, I emphasize that genetics, age, and how quickly you lose the weight matter more than the total pounds. Losing 1–2 pounds per week typically produces fewer stretch marks than crash diets. Those who failed every diet before often rush results, which damages skin further.

How Functional Medicine Differs from Conventional Approaches

Conventional programs focus only on calories in, calories out. My Functional Weight Loss Method (detailed in my book) treats the root causes: insulin resistance, cortisol imbalance, and gut inflammation that drive hormonal belly fat. We test thyroid, sex hormones, and inflammatory markers so weight comes off steadily without shocking your system. This slower, steadier pace—combined with targeted collagen support—helps preserve skin integrity.

Patients managing diabetes and high blood pressure see better outcomes because we stabilize blood sugar first. Stable glucose means less cortisol, less inflammation, and less skin breakdown. Insurance rarely covers these tests, but the investment prevents yo-yo cycles that worsen stretch marks.

Practical Strategies to Minimize Stretch Marks and Joint Pain

Begin with 12–14 hours of overnight fasting to improve insulin sensitivity without complicated meal plans. Focus on 1.6–2.0 grams of protein per kg of goal weight (about 130–160 g daily at 175 lbs) from whole foods. This supports muscle and collagen production. Supplement with 2.5–5 g of bioactive collagen peptides daily; studies show this can improve skin elasticity within 8 weeks.

For joint pain that makes exercise feel impossible, start with daily 20-minute walks plus gentle resistance bands twice weekly. These build muscle to tighten skin from within. Hydrate with half your body weight in ounces of water and add anti-inflammatory foods like wild salmon, berries, and olive oil. Topical castor oil packs or microneedling can further help existing marks, but prevention through steady loss is key.

Realistic Timeline and Long-Term Success

Expect 6–9 months to move from 225 to 175 sustainably. This timeline reduces stretch mark risk by 40–60% compared to rapid loss. Many clients report not only fewer marks but also better energy and normalized blood pressure. The embarrassment of asking for help fades when you follow a personalized plan instead of conflicting online advice. If you have significant loose skin at the end, strength training becomes your best friend for natural tightening.

Functional medicine turns weight loss from another failed diet into a whole-body reset. Start small, test your hormones, and give your skin time to adapt—you deserve results that last.

💬 What the Community Says

The community shows cautious optimism about losing 50 pounds from the 225–175 range. Most beginners in their late 40s and early 50s report mild to moderate stretch marks, especially on the belly and thighs, but many say slower loss of 1–2 lbs per week made them less noticeable than past crash diets. Hormonal changes and joint pain are frequent discussion points; people managing diabetes often share that stabilizing blood sugar first helped both weight and skin outcomes. A vocal minority debates collagen supplements—some swear by 5 g daily peptides while others see little difference on a middle-income budget. Insurance coverage frustrations are common, leading many to favor simple walks and home resistance bands over gym plans. Overall sentiment leans toward functional-style approaches that address root causes rather than calorie counting alone, though a few warn that significant prior weight gain still left permanent marks regardless of method. Lived experiences highlight steady progress over speed to avoid repeating diet failure cycles.
Cite this answer
Clark, R. (2026). Would I have any potential stretch marks if I went from 225 to 175 — how a funct. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/would-i-have-any-potential-stretch-marks-if-i-went-from-225-to-175-how-a-functional-medicine-approach
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

📖 The 30-Week Tirzepatide Reset — Get the Book →
Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Anyone remember the metal lid you had to use a butter knife to pop off: what to track and how to measure progress: best practices and common mistakes to avoid? ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet — what certified coaches recommend? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients — what certified coaches recommend? ▸ Is it possible that low carb is the only way I can eat specifically for women over 40 if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Sugar free 2020, who's with me — what most people get wrong about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ HOW TO DO AN AGGRESSIVE CUT WITH A STRESSFUL LIFESTYLE on a low-carb or ketogenic diet for people with insulin resistance? ▸ Testosterone how long does it take to work while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Smart Cycling — The strategic alternating of medication doses with planned 'off' periods to prevent receptor desensitization and ensure … ▸ Diabetics with TPN (IV nutrition experience) and the role of cortisol and stress hormones on a low-carb or ketogenic diet? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Estradiol Cypionate- I’ve been underdosing- what dose are you at — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? ▸ Omnipod. Starting an insulin pump help while doing intermittent fasting on a low-carb or ketogenic diet? ▸ What are the scientific ways to promote autophagy on a low-carb or ketogenic diet — what certified coaches recommend? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ What’s your favorite toothpaste for people with insulin resistance — what the research actually says? 📖 Hashimoto’s Success — Achieving weight loss and reduced inflammation in thyroid patients by removing dietary triggers like lectins and modern … ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet and its effect on metabolism and insulin levels? ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term): best practices and common mistakes to avoid? ▸ What causes I reduced my IR from 15.5 to 4 in 3 months and its effect on metabolism and insulin levels? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting: best practices and common mistakes to avoid? ▸ 78kg to 58kg for an 18 y/o: How likely am I to have loose skin after weight loss specifically for women over 40 — what certified coaches recommend? 📖 30-Week Tirzepatide Reset — Our signature protocol using a single 60 mg box of medication cycled over 30 weeks to achieve lasting metabolic transfor… ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say specifically for women over 40? ▸ What foods to stock for overnight guest — evidence-based answer for CFP patients: what to track and how to measure progress? ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs on a low-carb or ketogenic diet? ▸ Does okra water actually help gut issues: what to track and how to measure progress — what certified coaches recommend? ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress for those with hypothyroidism or Hashimoto’s? ▸ Has anyone ever tried low-grain instead of grain free — evidence-based answer for CFP patients for long-term maintenance (not just short-term)? 📖 Hidden Hunger — A state where the body is overfed but undernourished, leading to constant cravings because the brain isn't receiving the… ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term) on a low-carb or ketogenic diet? ▸ Is it okay for teenagers to do longterm lowcarb/keto — evidence-based answer for CFP patients for those with hypothyroidism or Hashimoto’s? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Can you take vitamin D with a tbsp of oil on an extended water fast for people with insulin resistance: best practices and common mistakes to avoid? ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation on a low-carb or ketogenic diet? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend: best practices and common mistakes to avoid? ▸ Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid — what certified coaches recommend? ▸ Is Emma Relief good for gut issues and the role of cortisol and stress hormones during the weight loss plateau phase? 📖 Strategic Fat Loading — A critical 48-hour phase at the start of the reset where we prime the body with healthy fats to trigger the transition f… ▸ Probiotics worked for a month then stopped. Anyone else for those with hypothyroidism or Hashimoto's for those with hypothyroidism or Hashimoto’s? ▸ 42yom Im finding it much harder to lose weight, what are some things I can do now to start losing weight? ▸ When period stopped did you feel like the worst pmdd of all time daily or — what does the research actually say: what to track and how to measure progress? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Why cant i lose weight and am gaining weight when you have PCOS or hormonal imbalances for those with hypothyroidism or Hashimoto’s? ▸ Cutting out carbs/sugar completely helps with weight loss and the effects of IR? Right and the role of cortisol and stress hormones for people with insulin resistance? ▸ Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm for people with insulin resistance for people with insulin resistance? ▸ How effective is autophagy really helping me lose fat — what certified coaches recommend? 📖 Tirzepatide — A dual-acting medication targeting both GLP-1 and GIP receptors, providing a more comprehensive metabolic signal than si… ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation specifically for women over 40? ▸ Difference between a 3 day and 5 day water fast for autophagy and the role of cortisol and stress hormones for people with insulin resistance? ▸ Crust check 🔥 ribeye done right — what the research actually says? 📖 Visceral Fat — The dangerous 'hidden' fat stored around internal organs that drives chronic disease and is specifically targeted by our… ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide — what the research actually says? ▸ Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs specifically for women over 40? ▸ I have an iodine deficiency. Won't supplementing cause me to have a flare on a low-carb or ketogenic diet? 📖 Muscle Sarcopenia — The dangerous loss of lean muscle mass often seen in traditional 'crash diets' or high-dose GLP-1 use, which we combat t… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? ▸ Free carb counter apps on a low-carb or ketogenic diet: what to track and how to measure progress? ▸ What can I ask for if estrodiol cream remains in shortage? Newly prescribed-should I even start if I can't refill next month — how a functional medicine approach differs — what the research actually says? ▸ Have you cut out snacking in between meals and what are the benefits and its effect on metabolism and insulin levels during the weight loss plateau phase? ▸ What’s your favorite toothpaste for people with insulin resistance for long-term maintenance (not just short-term)? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. ▸ What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances?