Expert Q&A

Why am I not losing weight despite being consistent with diet and exercise for people with insulin resistance

Understanding Insulin Resistance and Its Impact on Weight Loss

If you're over 45, dealing with insulin resistance, and still not seeing the scale move despite consistent efforts, you're not alone. In my years guiding thousands through the CFP Weight Loss method, I've found that standard diet and exercise advice fails when insulin resistance is in play. Your cells don't respond properly to insulin, causing your pancreas to pump out more, which signals your body to store fat—especially around the belly. Hormonal changes in perimenopause and menopause amplify this, making weight loss feel impossible even when calories are controlled.

Common Hidden Reasons You're Not Losing Weight

Consistency is key, but hidden factors sabotage progress. First, chronic high insulin levels block fat burning. Even "healthy" carbs like whole grains can spike blood sugar if your sensitivity is low. Second, joint pain often leads to lower intensity workouts, limiting calorie burn and muscle building. Third, metabolic adaptation occurs after repeated dieting—your body lowers energy expenditure to protect itself. Many also underestimate portion creep or liquid calories. Finally, stress and poor sleep raise cortisol, which works against insulin sensitivity. My book, The CFP Weight Loss Solution, details how these interplay with diabetes and blood pressure management.

Practical Strategies to Overcome Insulin Resistance

Start by prioritizing protein and fiber at every meal—aim for 30g protein to stabilize blood sugar. Focus on low-glycemic foods: non-starchy vegetables, healthy fats like avocado, and moderate berries. Time your carbs around workouts if possible. For exercise, begin with joint-friendly activities: 20-30 minute walks after meals to improve glucose uptake, plus resistance bands twice weekly to build muscle without strain. Track fasting insulin levels with your doctor—below 10 uU/mL is ideal. Intermittent fasting, like 12-14 hour overnight windows, can reset sensitivity without complex plans. Supplement smartly: berberine (500mg 2-3x daily) and chromium often help, but consult your physician, especially with medications.

Creating Sustainable Habits for Long-Term Success

The CFP approach emphasizes small, consistent changes over perfection. Batch-prep simple meals like egg muffins with veggies or salmon salads—no hour-long cooking required. Walk while on calls to fit movement in. Address emotional eating rooted in past diet failures by reframing this as metabolic repair, not another restriction. Many see 1-2 pounds weekly once insulin drops, plus better energy and joint comfort. Insurance barriers? Focus on affordable whole foods and home routines. You're not failing—you just need the right insulin-focused roadmap. Thousands in our community have reversed prediabetes and shed stubborn weight this way. Start today with one change: a post-dinner walk and protein-first breakfast.

💬 What the Community Says

In online forums and support groups, many in their late 40s to mid-50s express deep frustration that standard calorie deficits and gym routines yield zero results when insulin resistance or PCOS is involved. Most report hitting plateaus after initial water weight loss, with joint issues making HIIT impossible and doctors dismissing concerns unless labs show full diabetes. A common debate centers on low-carb versus Mediterranean approaches—some swear by keto for quick drops in blood sugar, while others find it unsustainable long-term and prefer balanced plates with walking. Lived experiences highlight relief from discovering fasting insulin tests, as regular A1C often misses the problem. Many feel embarrassed seeking help but share wins from adding strength training at home or using berberine after failed diets. The community is split on supplements versus food-first methods, yet most agree hormonal shifts make this stage uniquely difficult compared to earlier decades. Overall, there's strong support for practical, low-time-commitment strategies that fit busy middle-income lives without relying on expensive programs insurance won't cover.
Clark, R. (2026). Why am I not losing weight despite being consistent with diet and exercise for p. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/why-am-i-not-losing-weight-despite-being-consistent-with-diet-and-exercise-for-people-with-insulin-resistance
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
Any Links Between Autophagy & Eye Disease Reversing when you have PCOS or hormonal imbalances for people with insulin resistance? Starting my second extended fast tomorrow. Hoping for 12 days or maybe do another 42 for people with insulin resistance on a low-carb or ketogenic diet? How good is it if I still drink (sugar free) soda for those with hypothyroidism or Hashimoto's for those with hypothyroidism or Hashimoto’s? When you get your microdose calculations wrong for the Monday morning meeting for people with insulin resistance if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Metabolic Flexibility — The body’s ability to efficiently switch between burning carbohydrates and burning stored body fat based on availability… Does having no thyroid affect how my body responds to fasting and the role of cortisol and stress hormones if you're on a GLP-1 like semaglutide or tirzepatide? Can anyone help me with my pelvic ultrasound results ? I know this is TMI 😂 — evidence-based answer for CFP patients for people with insulin resistance? How to induce autophagy without fasting for a long time — what do certified weight loss coaches recommend on a low-carb or ketogenic diet? How I cured my bad breath. Especially helpful for people with sinus issues: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Paleo brownies/sweets that ship all over usa: how to talk to your doctor about this specifically for women over 40? 📖 Gut Microbiome Repair — The restoration of healthy intestinal bacteria through the removal of lectins and grains, essential for long-term weight… How do you guys manage stress — what does the research actually say: best practices and common mistakes to avoid? Diabetics with TPN (IV nutrition experience) on a low-carb or ketogenic diet if you're on a GLP-1 like semaglutide or tirzepatide? Depressive symptoms from non-stick air fryer — what do certified weight loss coaches recommend if you're on a GLP-1 like semaglutide or tirzepatide? Stacking NMN with TMG, what's your morning fasted protocol look like for people with insulin resistance while doing intermittent fasting? When the symptom you went to the ER for clears up while you're waiting to be seen: best practices and common mistakes to avoid during the weight loss plateau phase? How do you stop the "I already messed up today" spiral while doing intermittent fasting during the weight loss plateau phase? If you have a recently found thyroid nodule — would anyone be open to sharing what the first few weeks were like if you're on a GLP-1 like semaglutide or tirzepatide specifically for women over 40? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… Got to “goal weight” but not really. Anyone else try to do a cushion on a low-carb or ketogenic diet for long-term maintenance (not just short-term)? Being underweight, panic and anxiety. Recently got thyroid lab tested: best practices and common mistakes to avoid while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Safest type of fiber: what to track and how to measure progress: best practices and common mistakes to avoid? After losing weight, does it feel like you could do anything — evidence-based answer for CFP patients if you're on a GLP-1 like semaglutide or tirzepatide? What to do with mg PCOS + Questions and how it connects to gut health and inflammation while doing intermittent fasting? Gluten. I love it. How long to find out if it hates me: best practices and common mistakes to avoid if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Smart Cycling — The strategic alternating of medication doses with planned 'off' periods to prevent receptor desensitization and ensure … What is the connection between I reduced my IR from 15.5 to 4 in 3 months when you have PCOS or hormonal imbalances? Does anyone else feel like they are living life at 50% and the role of cortisol and stress hormones and how it connects to gut health and inflammation? What a month of paleo has done for me while doing intermittent fasting and its effect on metabolism and insulin levels? When period stopped did you feel like the worst pmdd of all time daily or while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Anyone else feel this way and the role of cortisol and stress hormones and its effect on metabolism and insulin levels? Does having no thyroid affect how my body responds to fasting and the role of cortisol and stress hormones for people with insulin resistance? 📖 Amylopectin A — The specific starch found in modern wheat that causes rapid, dangerous spikes in blood glucose and promotes belly fat st… Can Maintenance Phase do an episode about pregnancy weight gain — what do certified weight loss coaches recommend if you're on a GLP-1 like semaglutide or tirzepatide? Why are peptides suddenly everywhere in 2026 when most of them have been around for 20 or 30 years — what do certified weight loss coaches recommend specifically for women over 40? Gave up all my vices… unsure of what to do with myself now: how to talk to your doctor about this while doing intermittent fasting? Will doing omad 2-3 times a week get rid of it or reduce loose skin? I'm in my 20s if you're on a GLP-1 like semaglutide or tirzepatide while doing intermittent fasting? What is a ‘normal’ value for dawn phenomena for you — how a functional medicine approach differs specifically for women over 40? What is the connection between I reduced my IR from 15.5 to 4 in 3 months for people with insulin resistance? 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Has anyone stopped HRT and then restarted it for people with insulin resistance and how it connects to gut health and inflammation? I lost 100#s using cutting calories and exercising, 10 to 15,000 steps, and I soon plateaued and I was so hungry. Do you know any good empirical studies on LCHF and its effect on metabolism and insulin levels when you have PCOS or hormonal imbalances? When Someone Paid by Credit Card, We Had to Drag Out This — what most people get wrong about this and how it connects to gut health and inflammation? 📖 High-Dose Dependency — The pharmaceutical trap of staying on maximum medication doses indefinitely, which we avoid through our smart cycling me… Do you follow the food order recommendation for those with hypothyroidism or Hashimoto’s? When you want something sweet but still try to keep things somewhat low-carb for long-term maintenance (not just short-term) and how it connects to gut health and inflammation? Why is this ruining my life? Doctor's don't take me seriously. 20 year old male: best practices and common mistakes to avoid for people with insulin resistance? How it's going for me and how BMI has betrayed the tall girlies: what to track and how to measure progress while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Anybody else wake up after 5-6 hours because their lower back starts hurting if you're on a GLP-1 like semaglutide or tirzepatide and how it connects to gut health and inflammation? What's a physical thing you can do TODAY that you couldn't do at 40 for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. After losing weight, does it feel like you could do anything — evidence-based answer for CFP patients when you have PCOS or hormonal imbalances? Did an ultrasound and i saw two comments from the result. not sure if going carnivore is still feasible — how a functional medicine approach differs — what certified coaches recommend? How did I not get a heads up? I now make it my goal to help, support and inform others heading towards menooause and its effect on metabolism and insulin levels — what certified coaches recommend? Dark(ish) areas for stargazing during the weight loss plateau phase for long-term maintenance (not just short-term)? 📖 Cellular Detox — The process of clearing out metabolic waste and reducing cellular stress to allow for more efficient energy production a… Not a whingeing post. Just looking for some guidance.. I started IF with great success. I felt energised & found making note of the fasting stages really motivational. I had a break from IF: how to talk to your doctor about this for people with insulin resistance? So a lack of thyroid right while doing intermittent fasting when you have PCOS or hormonal imbalances?