Expert Q&A

Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturally. Advice? :) for people with insulin resistance?

Transitioning from Mounjaro to Natural Metabolic Reset

Congratulations on losing 13kg with Mounjaro—that's a solid start. The key now is shifting from medication dependency to true metabolic freedom. In my book The 30-Week Tirzepatide Reset, I outline exactly how to do this for people battling insulin resistance. Your body can heal and regulate hunger signals, blood sugar, and fat storage once you remove grains, lectins, ultra-processed carbs, and toxins while adding targeted habits.

Most patients regain weight after stopping GLP-1s because they never addressed root causes like chronic inflammation and broken hypothalamic function. My protocol prevents this with three 70-day cycles that cycle low-dose tirzepatide intelligently if needed, but emphasize real-food eating, detox support, and movement you can sustain even with joint pain.

Core Framework: The 30-Week Tirzepatide Reset Protocol

Follow the 69 Transformation Steps for a clear daily roadmap. Start with our lectin-free low-carb diet—221 recipes that stabilize blood sugar without complex meal plans. Focus on proteins, healthy fats, and non-starchy vegetables while eliminating the top inflammatory triggers that worsen insulin resistance. Pair this with our targeted Drops: Brown Detox Drops to clear toxins, Blue for natural hunger control, and Pink to support fat loss.

Incorporate Japanese-style walking intervals—short, gentle bursts that fit busy schedules and ease joint pain. Add red light therapy sessions through our Unlimited Red Bed Club to reduce inflammation and improve cellular energy. Track body composition, not just scale weight, to celebrate non-scale victories like better energy, looser clothes, and improved labs for diabetes and blood pressure.

Smart Cycling and Avoiding Common Pitfalls

If your insulin resistance markers remain elevated, consider one strategic low-dose tirzepatide cycle as outlined in the book rather than staying on high doses forever. The goal is metabolic reset, not lifelong injections. Avoid the two biggest mistakes: relying solely on medication without rebuilding habits, and obsessing over the scale instead of how you feel. Hormonal changes in your 40s and 50s make this harder, but the protocol accounts for that with chaotic intermittent fasting in maintenance phases.

Patients like John, who dropped his A1C from 7.8 to 6.2 and came off diabetes meds while losing 40 pounds total, show what's possible. He used the exact lectin-free approach, Detox Drops, daily walks, and red light—then maintained with the habits he built.

Building Lifelong Metabolic Freedom

Sustainable success means your body wants to stay lean naturally. Begin with a 7-day detox using the Brown Drops, then move through the cycles focusing on sleep, stress reduction, and simple routines that fit middle-income budgets and time constraints. Insurance rarely covers these programs, but the one-time investment in real tools and knowledge pays off by ending yo-yo dieting. Thousands have lost 30-90 pounds and kept it off—this can be your last reset.

💬 What the Community Says

People in midlife forums often celebrate initial Mounjaro losses like 13kg but express anxiety about the transition off the medication, especially with stubborn insulin resistance and past diet failures. Many share stories of regaining weight quickly without lifestyle changes, leading to frustration over joint pain limiting exercise and conflicting advice on carbs versus keto. A common theme is relief at finding structured protocols that include detox aids and gentle movement instead of gym intimidation. The community debates long-term GLP-1 use versus natural maintenance, with most agreeing that lectin-free or low-carb real-food approaches help stabilize blood sugar and energy. Insurance denials and time constraints fuel discussions around affordable, simple habits like walking intervals and red light. Success stories of sustained loss and improved A1C inspire, though a vocal minority warns against expecting miracles without consistent daily effort. Overall sentiment leans hopeful for those who combine meds strategically with root-cause fixes.
Cite this answer
Clark, R. (2026). Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturall. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/where-to-go-from-here-i-lost-13kg-on-mounjaro-but-i-am-doing-the-rest-naturally-advice-for-people-with-insulin-resistance
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

📖 The 30-Week Tirzepatide Reset — Get the Book →
Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term) on a low-carb or ketogenic diet? ▸ What foods to stock for overnight guest — evidence-based answer for CFP patients: what to track and how to measure progress? ▸ The cost of meat is soaring, especially beef. What are y’all doing to stay on budget on a low-carb or ketogenic diet? ▸ How long does it take to Is Autophagy? 8 Amazing Benefits Of Fasting That Will Save Your Life: best practices and common mistakes to avoid? ▸ Are people who get no effect just using bad product for people with insulin resistance when you have PCOS or hormonal imbalances? ▸ Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid — what certified coaches recommend? 📖 Metabolic Reset — The process of retraining your body to utilize stored fat for fuel and regulating hunger hormones so you can maintain yo… ▸ Did L. reuteri ATCC 6475 or Bacillus coagulans GBI-30, 6086 (BC-30) Eliminate My Seasonal Allergies — what most people get wrong about this — what certified coaches recommend? ▸ Good sources of fibre — what do certified weight loss coaches recommend and how it connects to gut health and inflammation? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting: best practices and common mistakes to avoid? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? 📖 Anti-Inflammatory Protocol — A way of eating that prioritizes whole foods and eliminates triggers to quiet the internal 'fire' that prevents fat cell… ▸ Is Emma Relief good for gut issues and the role of cortisol and stress hormones during the weight loss plateau phase? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and how it connects to gut health and inflammation? ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Sterilized soybean sprout — how a functional medicine approach differs: best practices and common mistakes to avoid? 📖 Autophagy — The body's natural 'housecleaning' process that occurs during fasting or low-insulin states, promoted during our mainten… ▸ Can chicken and beef tallow replace beef for people with insulin resistance: what to track and how to measure progress? ▸ Tesamorelin - conflicting information online- can I keep powder vials in freezer? Can I keep reconstituted vials in fridge — what do certified weight loss coaches recommend for those with hypothyroidism or Hashimoto’s? ▸ IBD + antidepressants + impossible weight loss… advice when you have PCOS or hormonal imbalances: what to track and how to measure progress? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Estradiol Cypionate- I’ve been underdosing- what dose are you at — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? ▸ Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm for people with insulin resistance for people with insulin resistance? ▸ Were any of you guys fans of Journey? How big were they — what the research actually says? ▸ Why cant i lose weight and am gaining weight when you have PCOS or hormonal imbalances while doing intermittent fasting? 📖 Muscle Sarcopenia — The dangerous loss of lean muscle mass often seen in traditional 'crash diets' or high-dose GLP-1 use, which we combat t… ▸ Free carb counter apps on a low-carb or ketogenic diet: what to track and how to measure progress? ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting on a low-carb or ketogenic diet? ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet — what certified coaches recommend? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say specifically for women over 40? ▸ I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Difference between a 3 day and 5 day water fast for autophagy and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? 📖 Caloric Deficit Myth — The false belief that weight loss is purely 'math'; we focus on hormonal signaling rather than just counting calories to… ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? ▸ LDN is changing my life, will this last: best practices and common mistakes to avoid: what to track and how to measure progress? ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs on a low-carb or ketogenic diet? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this: best practices and common mistakes to avoid? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ My weight loss progress so far as a 23 year male who stared eating less unhealthy and does little to moderate exercise. Am I doing well — evidence-based answer for CFP patients for people with insulin resistance? 📖 Tirzepatide Micro-Dosing — The practice of using the lowest effective dose to achieve results, minimizing side effects while maximizing the longevi… ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term): best practices and common mistakes to avoid? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide — what certified coaches recommend? ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide for long-term maintenance (not just short-term)? ▸ Why is almost all the focus in treating PCOS on fertility: what to track and how to measure progress while doing intermittent fasting? ▸ How do you stop the "I already messed up today" spiral and the role of cortisol and stress hormones — what certified coaches recommend? ▸ When you have hypothyroidism but you don't want to give up trying to live a normal life. 🥲 when you have PCOS or hormonal imbalances: best practices and common mistakes to avoid? ▸ How I started this year vs. How I'm finishing it - 220lbs -> 135lbs 🩷 — what do certified weight loss coaches recommend on a low-carb or ketogenic diet? 📖 Visceral Fat — The dangerous 'hidden' fat stored around internal organs that drives chronic disease and is specifically targeted by our… ▸ What are the wegovy doses in order on a low-carb or ketogenic diet if you're on a GLP-1 like semaglutide or tirzepatide? ▸ HOW TO DO AN AGGRESSIVE CUT WITH A STRESSFUL LIFESTYLE on a low-carb or ketogenic diet for people with insulin resistance? ▸ Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better specifically for women over 40? ▸ Who still goes to steeplechase — what do certified weight loss coaches recommend for long-term maintenance (not just short-term)? 📖 Amylopectin A — The specific starch found in modern wheat that causes rapid, dangerous spikes in blood glucose and promotes belly fat st… ▸ Im eating so well that I accidently put my body in ketosis and how it connects to gut health and inflammation: best practices and common mistakes to avoid? ▸ Good calorie amount? Advice to get high volume low cal and more protein when you have PCOS or hormonal imbalances — what the research actually says? ▸ How I Lost 22lbs in 3 Months (155→133lbs at 5'8") after not being able to lose weight for a long time if you're on a GLP-1 like semaglutide or tirzepatide during the weight loss plateau phase?