Expert Q&A

Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturally. Advice? :) during the weight loss plateau phase

Understanding Your Post-Mounjaro Plateau

Congratulations on losing 13kg with Mounjaro—that's a significant achievement, especially when managing diabetes and blood pressure. Now entering the weight loss plateau phase naturally is common because your body adapts to lower calories and altered hormones. After GLP-1 medications like Mounjaro, metabolism can slow by up to 15-20% as it defends against further loss. Hormonal shifts in your 45-54 age range, particularly perimenopause or menopause for women, compound this by increasing insulin resistance and cortisol.

In my book The CFP Weight Loss Method, I emphasize recalibrating without panic. Plateaus typically last 3-6 weeks; view this as your body's reset rather than failure. Track non-scale victories like improved energy, better blood sugar readings (aim for fasting glucose under 100 mg/dL), and reduced joint pain.

Nutrition Adjustments for Natural Momentum

Stop cycling through conflicting advice—focus on protein-first eating. Consume 1.6-2.0 grams of protein per kg of current body weight daily (about 100-140g for most in your range) to preserve muscle and boost satiety. This counters the muscle loss that often follows medication-assisted loss. Swap complex meal plans for my simple plate method: ½ non-starchy vegetables, ¼ lean protein, ¼ complex carbs like quinoa or sweet potato.

Address hormonal changes by incorporating anti-inflammatory foods—think fatty fish twice weekly for omega-3s, which can reduce joint inflammation by 25%. Time your carbs around activity rather than eliminating them. Avoid drastic cuts below 1,500 calories; this triggers metabolic slowdown. Instead, cycle calories: 5 days at maintenance level (use an online TDEE calculator adding 200 calories to your estimated needs), 2 days at 300-calorie deficit.

Joint-Friendly Movement and Lifestyle Tweaks

Exercise doesn't need to be impossible with joint pain. Start with 10-minute daily walks, progressing to water aerobics or resistance bands 3x weekly. These build muscle without stress—each pound of muscle burns 6-10 extra calories daily at rest. In The CFP Weight Loss Method, I outline a beginner “Movement Ladder” that starts seated and scales up, perfect when insurance won't cover formal programs.

Prioritize sleep (7-9 hours) and stress reduction; even 10 minutes of daily meditation lowers cortisol, which directly impacts belly fat storage. Stay hydrated at 3 liters daily—dehydration alone can stall progress by mimicking hunger.

Long-Term Sustainability and When to Seek Support

Measure progress every 2 weeks with waist circumference (aim to lose 1-2cm monthly during plateaus) rather than daily weigh-ins. If stalled beyond 8 weeks, consider a 1-week maintenance phase at true calorie balance before resuming a mild deficit. You're not alone feeling embarrassed about obesity or overwhelmed—many in our community share these exact struggles.

Breakthroughs happen when consistency meets self-compassion. You've already proven you can lose weight naturally post-Mounjaro; now refine the approach using these targeted strategies for lasting hormonal balance and metabolic health.

💬 What the Community Says

The community shows mixed but hopeful sentiment around transitioning off Mounjaro to natural weight maintenance. Many in the 45-54 age group report similar 10-15kg losses followed by stubborn plateaus lasting 4-8 weeks, often blaming hormonal shifts and slower metabolism. Most practitioners find protein prioritization and switching to non-scale measurements helpful, with several noting joint-friendly activities like swimming finally became sustainable after initial resistance. A vocal minority debates whether brief medication "tune-ups" are necessary versus pure natural methods, while others share success with calorie cycling and stress management. Common experiences include frustration with conflicting online advice and embarrassment asking for help, but encouragement around celebrating blood sugar improvements and energy gains is widespread. Beginners frequently mention feeling overwhelmed yet inspired by stories of gradual progress without gym schedules.
Clark, R. (2026). Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturall. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/where-to-go-from-here-i-lost-13kg-on-mounjaro-but-i-am-doing-the-rest-naturally-advice-during-the-weight-loss-plateau-phase
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ What actually helps with the dryness when you have PCOS or hormonal imbalances while doing intermittent fasting? ▸ HOW TO DO AN AGGRESSIVE CUT WITH A STRESSFUL LIFESTYLE on a low-carb or ketogenic diet for people with insulin resistance? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients specifically for women over 40? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients while doing intermittent fasting? 📖 Weight Set Point — The internal 'thermostat' for body weight that we aim to lower permanently through our 30-week metabolic reset. ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ When the fatigue is real: how to talk to your doctor about this for people with insulin resistance? ▸ 225lbs 5’10, is it possible for me to lose weight starting at 2200 calories a day when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? ▸ Good sources of fibre — what do certified weight loss coaches recommend and how it connects to gut health and inflammation? 📖 Insulin Resistance — A condition where your cells stop responding to insulin, locking fat in storage; our protocol is designed to unlock thes… ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide: best practices and common mistakes to avoid? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Does the fear of gaining ever go away for those with hypothyroidism or Hashimoto's and its effect on metabolism and insulin levels? ▸ Compression socks. Worth it? Any recs — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? 📖 Phase 2: Aggressive Loss — A 40-day window of focused fat loss supported by low-dose medication and a specific lectin-free, low-carb nutritional fr… ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide for long-term maintenance (not just short-term)? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and its effect on metabolism and insulin levels? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend: best practices and common mistakes to avoid? 📖 Hormonal Chaos — The internal state of imbalance caused by modern grains and refined carbs that overrides willpower and forces the body t… ▸ Does drinking Sparkling Ice (flavored sparkling water - 5 calories per bottle) during my fasting window break my fast and the role of cortisol and stress hormones during the weight loss plateau phase? ▸ How does chasing skinny ever get old for long-term results while doing intermittent fasting? ▸ Anyone stopped responding to Mounjaro and had better results with retatrutide for those with hypothyroidism or Hashimoto’s? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet for long-term maintenance (not just short-term)? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Good calorie amount? Advice to get high volume low cal and more protein when you have PCOS or hormonal imbalances — what the research actually says? 📖 Autophagy — The body's natural 'housecleaning' process that occurs during fasting or low-insulin states, promoted during our mainten… ▸ Will eating meintenance calories make me lose weight for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ What can I ask for if estrodiol cream remains in shortage? Newly prescribed-should I even start if I can't refill next month — how a functional medicine approach differs — what the research actually says? ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide — what certified coaches recommend? ▸ Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid specifically for women over 40? 📖 Cellular Detox — The process of clearing out metabolic waste and reducing cellular stress to allow for more efficient energy production a… ▸ What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances when you have PCOS or hormonal imbalances? ▸ Anyone know where to purchase pork rind tortillas — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? 📖 CICO (Calories In, Calories Out) — An outdated model of weight loss that ignores the role of hormones; we challenge this by focusing on food quality and ho… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones for those with hypothyroidism or Hashimoto’s? ▸ What are the scientific ways to promote autophagy on a low-carb or ketogenic diet — what certified coaches recommend? ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting: what to track and how to measure progress? ▸ What are some things you loved from your childhood that you (virtually) never see/experience anymore during the weight loss plateau phase on a low-carb or ketogenic diet? 📖 The Clark Protocol — Our evidence-based framework that combines clinical nurse practitioner expertise with personal experience to solve the o… ▸ Estradiol Cypionate- I’ve been underdosing- what dose are you at — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say specifically for women over 40? ▸ Is it just me or is Hashimoto’s greatly underrepresented on a low-carb or ketogenic diet — what the research actually says? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this and its effect on metabolism and insulin levels? 📖 Gut-Brain Axis — The complex communication network between your digestive system and your brain that controls satiety, mood, and metaboli… ▸ Anyone remember the metal lid you had to use a butter knife to pop off: what to track and how to measure progress while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Has anyone felt better taking antidepressants instead of hrt — evidence-based answer for CFP patients — what certified coaches recommend? ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term) on a low-carb or ketogenic diet? ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better on a low-carb or ketogenic diet? ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation specifically for women over 40? ▸ Testosterone how long does it take to work while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Does mental health predict diabetes as much as BMI? Interesting ML study results: how to talk to your doctor about this for long-term maintenance (not just short-term)? 📖 Lectin-Free Living — Eliminating inflammatory plant proteins that damage the gut lining and trigger the autoimmune responses that often stall… ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet and its effect on metabolism and insulin levels? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Cutting out carbs/sugar completely helps with weight loss and the effects of IR? Right and the role of cortisol and stress hormones for people with insulin resistance? 📖 Diabetes Reversal — The clinical goal of restoring normal blood sugar levels and insulin function, as seen in patients like John who no long… ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs on a low-carb or ketogenic diet? ▸ Crust check 🔥 ribeye done right — what the research actually says? ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress for those with hypothyroidism or Hashimoto’s? 📖 Inflammatory Markers — Clinical indicators like CRP that we monitor to ensure the body is moving from a state of disease to a state of vibrant … ▸ How do you stop the "I already messed up today" spiral and the role of cortisol and stress hormones — what certified coaches recommend?