Expert Q&A

Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturally. Advice? :) and the role of cortisol and stress hormones

Congratulations on Your 13kg Loss – Now Protect It Naturally

Losing 13kg on Mounjaro is a major win, especially with your hormonal changes and joint pain. The real challenge begins now: transitioning to sustainable natural weight loss without medication. In my book The CFP Method, I emphasize building metabolic resilience through simple daily habits that address root causes like stress, insulin resistance, and inflammation. Since insurance rarely covers these programs and time is limited, we'll focus on beginner-friendly strategies that fit middle-income lifestyles and manage diabetes and blood pressure alongside weight.

Practical Next Steps for Natural Maintenance

Start with a 12-week stabilization phase. Reduce processed carbs to under 100g daily while increasing protein to 1.6g per kg of body weight—this preserves muscle lost during rapid GLP-1 phases. Walk 30 minutes daily in two 15-minute sessions; this low-impact movement eases joint pain and improves blood sugar without gym intimidation. Track fasting insulin, not just glucose, aiming below 10 μU/mL. For busy schedules, prep one "CFP sheet pan meal" weekly: combine non-starchy vegetables, healthy fats, and lean protein roasted together. These small wins rebuild trust after past diet failures.

The Critical Role of Cortisol and Stress Hormones

Cortisol, your primary stress hormone, directly sabotages natural weight loss. Elevated levels from chronic stress promote abdominal fat storage, increase cravings, and impair thyroid function—worsening midlife hormonal shifts. Studies show cortisol spikes can raise blood pressure and blood sugar, complicating your diabetes management. In the CFP framework, we target this with "stress snacks": 5-minute breathwork (4-7-8 pattern) before meals to lower cortisol by up to 23%. Prioritize 7-8 hours sleep; even one poor night raises next-day cortisol 37%. If embarrassment keeps you from asking for help, remember community support reduces perceived stress dramatically.

Overcoming Overwhelm: Your Personalized CFP Roadmap

Ignore conflicting nutrition advice by following this rule: eat real food within a 10-12 hour window. Supplement wisely with magnesium glycinate (300mg nightly) to calm stress hormones and support joints. Reassess every 4 weeks using waist circumference (<35 inches for women, <40 for men) rather than scale weight. If progress stalls, investigate hidden inflammation from poor sleep or emotional eating. You've already proven you can succeed—now layer these habits to make results permanent. Thousands in our community have maintained 10-20kg losses naturally after medications by focusing on cortisol control first. Start today with one walk and one breathing session; momentum builds from there.

💬 What the Community Says

Users who lost 10-15kg on Mounjaro often share excitement turning to anxiety about regain once stopping the medication. Many in the 45-54 age group report cortisol-related plateaus, with stress from work and family life making natural maintenance feel impossible. A common theme is relief finding low-impact walking plans that don't aggravate joint pain, though opinions split on strict carb limits versus moderate approaches. Beginners frequently mention embarrassment seeking help, leading to solo experiments that sometimes backfire. Most appreciate simple meal prep ideas that fit real schedules and budgets, especially those managing blood pressure and diabetes. A vocal minority warns against ignoring sleep and stress, citing personal rebounds when life got chaotic. Overall sentiment leans hopeful but cautious, with repeated calls for realistic, non-gym strategies that address hormonal realities.
Clark, R. (2026). Where to go from here? I lost 13kg on mounjaro, but I am doing the rest naturall. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/where-to-go-from-here-i-lost-13kg-on-mounjaro-but-i-am-doing-the-rest-naturally-advice-and-the-role-of-cortisol-and-stress-hormones
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ How many were first diagnosed with OCD if you're on a GLP-1 like semaglutide or tirzepatide on a low-carb or ketogenic diet? ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say and its effect on metabolism and insulin levels? ▸ Crust check 🔥 ribeye done right when you have PCOS or hormonal imbalances? ▸ What can I ask for if estrodiol cream remains in shortage? Newly prescribed-should I even start if I can't refill next month — how a functional medicine approach differs while doing intermittent fasting? ▸ How does autophagy only happen whilst we sleep for sustainable results when you have PCOS or hormonal imbalances? 📖 Diabetes Reversal — The clinical goal of restoring normal blood sugar levels and insulin function, as seen in patients like John who no long… ▸ Sugar free 2020, who's with me — what most people get wrong about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Why cant i lose weight and am gaining weight when you have PCOS or hormonal imbalances for those with hypothyroidism or Hashimoto’s? ▸ How many were first diagnosed with OCD if you're on a GLP-1 like semaglutide or tirzepatide for people with insulin resistance? ▸ My weight loss progress so far as a 23 year male who stared eating less unhealthy and does little to moderate exercise. Am I doing well — evidence-based answer for CFP patients for people with insulin resistance? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients specifically for women over 40? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better specifically for women over 40? 📖 Modern Wheat Dangers — The hidden threat in hybridized grains that causes gut inflammation and spikes blood sugar more aggressively than pure t… ▸ Is Emma Relief good for gut issues and the role of cortisol and stress hormones during the weight loss plateau phase? ▸ Making me super tired and in a dreamy, chill, ready for a nap state for most of the day and its effect on metabolism and insulin levels for long-term maintenance (not just short-term)? ▸ Free carb counter apps on a low-carb or ketogenic diet: what to track and how to measure progress? ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Phase 1: Priming — The first 48 hours of a 70-day cycle focused on high-fat intake to prevent the brain from triggering a starvation respon… ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better on a low-carb or ketogenic diet? ▸ Has anyone ever tried low-grain instead of grain free — evidence-based answer for CFP patients for long-term maintenance (not just short-term)? ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? ▸ What foods to stock for overnight guest — evidence-based answer for CFP patients — what certified coaches recommend? ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances while doing intermittent fasting? ▸ What is your immediate go to for some relief during ha — what most people get wrong about this — what certified coaches recommend? 📖 Smart Cycling — The strategic alternating of medication doses with planned 'off' periods to prevent receptor desensitization and ensure … ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? ▸ LDN is changing my life, will this last: best practices and common mistakes to avoid for people with insulin resistance? ▸ Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm for people with insulin resistance for people with insulin resistance? ▸ Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs specifically for women over 40? ▸ How to calm my nerves down at doctors — what do certified weight loss coaches recommend if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Compression socks. Worth it? Any recs — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. ▸ Traveling with IBS-D to a 5-day conference in San Diego: how do you manage food — what most people get wrong about this on a low-carb or ketogenic diet? ▸ What’s your favorite toothpaste for people with insulin resistance — what the research actually says? ▸ Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ Why is almost all the focus in treating PCOS on fertility: what to track and how to measure progress while doing intermittent fasting? 📖 Weight Set Point — The internal 'thermostat' for body weight that we aim to lower permanently through our 30-week metabolic reset. ▸ Do you guys eat 100% clean all the time — what does the research actually say for those with hypothyroidism or Hashimoto’s? ▸ Weight loss without GLP-1 — what does the research actually say while doing intermittent fasting? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend — what certified coaches recommend? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… ▸ What can I ask for if estrodiol cream remains in shortage? Newly prescribed-should I even start if I can't refill next month — how a functional medicine approach differs — what the research actually says? ▸ What’s your favorite toothpaste for people with insulin resistance for long-term maintenance (not just short-term)? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? ▸ Beef/Beef organs protein powder: what to track and how to measure progress if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How do you handle social settings and conversations with other people — what does the research actually say on a low-carb or ketogenic diet? 📖 Metabolic Flexibility — The body’s ability to efficiently switch between burning carbohydrates and burning stored body fat based on availability… ▸ Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid specifically for women over 40? ▸ How much protein should I eat if I weigh 280 pounds and want to cut a 100 pounds of fat off of my body? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances when you have PCOS or hormonal imbalances? ▸ How are people using 10mg reta vials at low doses during the weight loss plateau phase — what the research actually says? ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting: what to track and how to measure progress? 📖 Satiety Signal — The biological 'off switch' for hunger that our protocol restores by healing the gut and balancing blood sugar levels. ▸ Will eating meintenance calories make me lose weight for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Lost weight not exactly willingly and everybody’s weird about it for long-term maintenance (not just short-term) — what the research actually says? ▸ Sugar free 2020, who's with me — what most people get wrong about this: what to track and how to measure progress?