Expert Q&A

What causes I finished 2023 vs 2025 while doing intermittent fasting?

The 2023 Success That Faded by 2025

When intermittent fasting first clicked for many in their mid-40s and 50s, the scale moved quickly. Typical early wins included dropping 15-25 pounds in 8-12 weeks through 16:8 or 18:6 windows, paired with lower carb intake. Energy seemed better, blood sugar stabilized, and joint pain eased enough to walk daily. By 2025, the same approach stalls or reverses. This pattern repeats in our clinic: patients lose, plateau, then regain 80% within 12-18 months. The core issue is that intermittent fasting alone does not address root causes like deepening insulin resistance, rising inflammation from lectins, accumulated environmental toxins, and shifting hormones during perimenopause or andropause.

Root Causes Behind the Regain

Modern diets high in grains, ultra-processed foods, and hidden lectins drive chronic low-grade inflammation that damages the hypothalamus and leptin signaling. Over time, even perfect fasting windows cannot overcome a metabolism programmed for fat storage. Hormonal changes in the 45-54 age group amplify this: declining estrogen or testosterone slows thyroid function and raises cortisol, making fat loss feel impossible despite consistent effort. Toxin burden from plastics and processed foods further disrupts metabolic freedom. Joint pain limits movement, insurance barriers prevent professional guidance, and conflicting nutrition advice leads to overwhelm. These factors explain why 2023 results evaporated by 2025.

The 30-Week Tirzepatide Reset Solution

In my book The 30-Week Tirzepatide Reset, we use three 70-day cycles combining low-dose tirzepatide cycling, a precise lectin-free low-carb meal plan with 221 recipes, targeted supplements like Brown Detox Drops, red light therapy via our Unlimited Red Bed Club, and Japanese-style walking intervals. This is not medication dependency. Tirzepatide is cycled intelligently to reset hunger signals and insulin sensitivity while real food, detox, and movement rebuild natural regulation. The 69 Transformation Steps provide a daily roadmap that fits busy middle-income schedules without complex gym plans. Patients track body composition instead of obsessing over the scale, celebrating non-scale victories like better blood pressure, A1C drops from 7.8 to 6.2, and sustained energy.

Real Patient Outcomes and Lasting Metabolic Freedom

Consider John, a 60-year-old with type 2 diabetes. Starting our protocol, he lost 40 pounds over 30 weeks, eliminated two medications, and maintained results using chaotic intermittent fasting in the maintenance phase. Similar stories show 30-90 pound losses without rebound when the full system is followed. The biggest mindset shift is moving from “I need shots forever” to trusting your body’s ability to self-regulate once modern obstacles are removed. Our approach prevents the two fatal mistakes: relying on medication alone and chasing quick fixes. Instead, it delivers sustainable weight loss by restoring hormonal balance and hypothalamic function so you keep the weight off naturally long after cycling ends.

💬 What the Community Says

The community shows a clear split between early intermittent fasting adopters who succeeded in 2023 and those frustrated by 2025 regain. Many in the 45-54 group report initial 15-30 pound losses followed by plateaus and rebound once life stress, hormonal shifts, or dietary creep returned. Practitioners frequently mention joint pain limiting exercise consistency and insurance denials blocking structured programs. A vocal minority praises adding GLP-1 medications like tirzepatide but debates long-term dependency versus cycling strategies. Lived experiences highlight lectin sensitivity, toxin overload, and conflicting keto versus fasting advice as major pain points. Most agree that simple fasting alone stopped working after the first year, leading many to seek integrated protocols that combine real food, detox support, and smart medication use for lasting results. Success stories focus on non-scale victories and metabolic improvements rather than just the number on the scale.
Clark, R. (2026). What causes I finished 2023 vs 2025 while doing intermittent fasting?. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/what-causes-i-finished-2023-vs-2025-while-doing-intermittent-fasting
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Anyone stopped responding to Mounjaro and had better results with retatrutide for those with hypothyroidism or Hashimoto’s? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this and its effect on metabolism and insulin levels? ▸ When the fatigue is real: how to talk to your doctor about this for people with insulin resistance? ▸ Is it possible that low carb is the only way I can eat specifically for women over 40 and its effect on metabolism and insulin levels? ▸ Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs and its effect on metabolism and insulin levels? ▸ Does mental health predict diabetes as much as BMI? Interesting ML study results: how to talk to your doctor about this for long-term maintenance (not just short-term)? 📖 Phase 1: Priming — The first 48 hours of a 70-day cycle focused on high-fat intake to prevent the brain from triggering a starvation respon… ▸ Diabetics with TPN (IV nutrition experience) and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs during the weight loss plateau phase? ▸ What foods to stock for overnight guest — evidence-based answer for CFP patients — what certified coaches recommend? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances when you have PCOS or hormonal imbalances? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's if you're on a GLP-1 like semaglutide or tirzepatide? 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… ▸ Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid specifically for women over 40? ▸ Estradiol Cypionate- I’ve been underdosing- what dose are you at — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? ▸ LDN is changing my life, will this last: best practices and common mistakes to avoid: what to track and how to measure progress? 📖 Hormonal Chaos — The internal state of imbalance caused by modern grains and refined carbs that overrides willpower and forces the body t… ▸ 78kg to 58kg for an 18 y/o: How likely am I to have loose skin after weight loss specifically for women over 40 — what certified coaches recommend? ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet and its effect on metabolism and insulin levels? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say on a low-carb or ketogenic diet? ▸ When you want something sweet but still try to keep things somewhat low-carb and how it connects to gut health and inflammation if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Refined Carbohydrates — Processed sugars and flours that strip the body of nutrients while driving the hormonal chaos responsible for the modern… ▸ Is tomato paste lectin free during the weight loss plateau phase while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Cutting out carbs/sugar completely helps with weight loss and the effects of IR? Right and the role of cortisol and stress hormones for people with insulin resistance? ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say specifically for women over 40? ▸ What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ What causes I reduced my IR from 15.5 to 4 in 3 months and its effect on metabolism and insulin levels? 📖 Hidden Hunger — A state where the body is overfed but undernourished, leading to constant cravings because the brain isn't receiving the… ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress for those with hypothyroidism or Hashimoto’s? ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ Making me super tired and in a dreamy, chill, ready for a nap state for most of the day and its effect on metabolism and insulin levels for long-term maintenance (not just short-term)? ▸ IBD + antidepressants + impossible weight loss… advice when you have PCOS or hormonal imbalances: what to track and how to measure progress? ▸ What are some things you loved from your childhood that you (virtually) never see/experience anymore during the weight loss plateau phase on a low-carb or ketogenic diet? ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Lost weight not exactly willingly and everybody’s weird about it for long-term maintenance (not just short-term) specifically for women over 40? 📖 Diabetes Reversal — The clinical goal of restoring normal blood sugar levels and insulin function, as seen in patients like John who no long… ▸ Traveling with IBS-D to a 5-day conference in San Diego: how do you manage food — what most people get wrong about this on a low-carb or ketogenic diet? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones for those with hypothyroidism or Hashimoto’s? ▸ When you want something sweet but still try to keep things somewhat low-carb and how it connects to gut health and inflammation on a low-carb or ketogenic diet? 📖 CICO (Calories In, Calories Out) — An outdated model of weight loss that ignores the role of hormones; we challenge this by focusing on food quality and ho… ▸ Can chicken and beef tallow replace beef — what do certified weight loss coaches recommend for those with hypothyroidism or Hashimoto’s? ▸ How to calm my nerves down at doctors — what do certified weight loss coaches recommend if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Anyone remember the metal lid you had to use a butter knife to pop off: what to track and how to measure progress: best practices and common mistakes to avoid? ▸ I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) — what the research actually says? ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation on a low-carb or ketogenic diet? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ When am I supposed to see a doctor, then and how it connects to gut health and inflammation specifically for women over 40? 📖 One Box Protocol — A revolutionary approach where we stretch one 60 mg box of tirzepatide across three metabolic phases, prioritizing long-… ▸ Omnipod. Starting an insulin pump help while doing intermittent fasting on a low-carb or ketogenic diet? ▸ Who still goes to steeplechase — what do certified weight loss coaches recommend for long-term maintenance (not just short-term)? ▸ Sugar free 2020, who's with me — what most people get wrong about this: what to track and how to measure progress? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients — what certified coaches recommend? 📖 Hashimoto’s Success — Achieving weight loss and reduced inflammation in thyroid patients by removing dietary triggers like lectins and modern … ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend — what certified coaches recommend? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How long until I start losing weight this way — how a functional medicine approach differs and its effect on metabolism and insulin levels? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting: what to track and how to measure progress? 📖 Inflammatory Markers — Clinical indicators like CRP that we monitor to ensure the body is moving from a state of disease to a state of vibrant … ▸ Why cant i lose weight and am gaining weight when you have PCOS or hormonal imbalances while doing intermittent fasting? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet when you have PCOS or hormonal imbalances?