Expert Q&A

I just want to give up... will it ever end, will things ever get better and the role of cortisol and stress hormones

Why It Feels Like It Will Never End

I've worked with thousands in their late 40s and early 50s who echo your exact words: "I just want to give up." The constant battle against the scale, especially when hormonal changes hit during perimenopause or andropause, creates a perfect storm. Joint pain makes movement feel impossible, diabetes and blood pressure add layers of complexity, and conflicting nutrition advice leaves you overwhelmed. The good news? Things absolutely can get better when you address the hidden driver most diets ignore: stress hormones.

The Role of Cortisol in Stubborn Weight Gain

Cortisol, your primary stress hormone, rises with chronic pressure from work, family, or even the frustration of past diet failures. In my book The Stress-Weight Connection, I explain how elevated cortisol signals your body to store fat—particularly around the midsection—while breaking down muscle. For middle-income Americans balancing jobs and health issues, this creates a cycle where stress eating feels like the only relief. Studies show cortisol levels can increase belly fat by up to 20% in midlife adults under persistent stress. It also disrupts insulin sensitivity, making blood sugar management harder if you're dealing with diabetes.

Breaking the Stress Hormone Cycle with Simple Strategies

Recovery starts with recognizing that quick-fix diets fail because they spike cortisol further. Instead, follow the CFP Weight Loss approach: begin with 10-minute daily walks that respect your joint pain—no gym required. Focus on protein pacing with 25-30 grams at each meal using affordable foods like eggs, Greek yogurt, and beans. This stabilizes blood sugar and reduces cravings without complex meal plans. Incorporate box breathing (4 seconds in, hold 4, out 4, hold 4) twice daily to lower cortisol by 15-25% within weeks. Track sleep—aim for 7 hours—as poor rest elevates stress hormones by 30%. These steps fit busy schedules and don't require expensive programs insurance won't cover.

Building Momentum and Seeing Real Change

Progress builds when you shift from self-criticism to consistent micro-habits. Many clients report 8-12 pounds lost in the first 6 weeks by managing cortisol first, then layering in light resistance bands for joint-friendly strength. Your body will respond once stress hormones normalize, improving energy, reducing inflammation, and making weight loss sustainable. It does end. Things get better—not through willpower alone, but by working with your physiology. Start today with one breathing session and one high-protein meal. You've survived every failed diet; now let's make this the one that succeeds.

💬 What the Community Says

In online forums and support groups for midlife weight loss, many in their 40s-50s express deep exhaustion with yo-yo dieting, often mentioning how stress and "cortisol belly" make progress feel impossible. A common thread is frustration with joint pain limiting exercise and insurance denying coverage for programs, leading to feelings of defeat. Most practitioners share stories of initial skepticism but note gradual wins from simpler routines like short walks and better sleep. There's lively debate around whether hormone testing helps or just adds expense. A vocal minority reports breakthrough moments once they addressed stress eating, though others warn that life stressors like work or family often derail efforts. Overall sentiment mixes hopelessness with cautious hope, with frequent requests for beginner-friendly, low-time-commitment tips that don't require drastic lifestyle overhauls.
Clark, R. (2026). I just want to give up... will it ever end, will things ever get better and the . *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/i-just-want-to-give-up-will-it-ever-end-will-things-ever-get-better-and-the-role-of-cortisol-and-stress-hormones
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Were any of you guys fans of Journey? How big were they — what the research actually says? ▸ Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm for people with insulin resistance for people with insulin resistance? ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs and how it connects to gut health and inflammation? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this: best practices and common mistakes to avoid? ▸ My weight loss progress so far as a 23 year male who stared eating less unhealthy and does little to moderate exercise. Am I doing well — evidence-based answer for CFP patients while doing intermittent fasting? ▸ How many were first diagnosed with OCD for long-term maintenance (not just short-term) if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Is it normal to lose weight then gain again when you have PCOS or hormonal imbalances for long-term maintenance (not just short-term)? 📖 Visceral Fat — The dangerous 'hidden' fat stored around internal organs that drives chronic disease and is specifically targeted by our… ▸ Tesamorelin - conflicting information online- can I keep powder vials in freezer? Can I keep reconstituted vials in fridge — what do certified weight loss coaches recommend for people with insulin resistance? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ Why is almost all the focus in treating PCOS on fertility: what to track and how to measure progress while doing intermittent fasting? 📖 Adipose Tissue Signaling — The way fat cells communicate with the brain; our goal is to fix these signals so the body stops defending an unnaturall… ▸ Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ Those of you with Reta experience how does this protocol look for people with insulin resistance when you have PCOS or hormonal imbalances? ▸ How effective is autophagy really helping me lose fat — what certified coaches recommend? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… ▸ When do you know to go to the hospital specifically for women over 40? ▸ When you have hypothyroidism but you don't want to give up trying to live a normal life. 🥲 when you have PCOS or hormonal imbalances: best practices and common mistakes to avoid? ▸ Why aren’t obesity medical breakthroughs a bigger deal and its effect on metabolism and insulin levels while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Does mental health predict diabetes as much as BMI? Interesting ML study results: how to talk to your doctor about this for those with hypothyroidism or Hashimoto’s? ▸ Testosterone how long does it take to work while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How does autophagy only happen whilst we sleep for sustainable results when you have PCOS or hormonal imbalances? ▸ I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) — what the research actually says? 📖 Lectin-Free Living — Eliminating inflammatory plant proteins that damage the gut lining and trigger the autoimmune responses that often stall… ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say and its effect on metabolism and insulin levels? ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress for those with hypothyroidism or Hashimoto’s? ▸ Will eating meintenance calories make me lose weight for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ Omnipod. Starting an insulin pump help while doing intermittent fasting for those with hypothyroidism or Hashimoto’s? ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide — what the research actually says? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ How much keto-ade should I safely drink: best practices and common mistakes to avoid and how it connects to gut health and inflammation? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say on a low-carb or ketogenic diet? 📖 Leptin Sensitivity — Restoring your brain's ability to hear the 'I am full' signal, which is often muted by high-sugar diets and systemic inf… ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation on a low-carb or ketogenic diet? ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term): best practices and common mistakes to avoid? ▸ Have you cut out snacking in between meals and what are the benefits and its effect on metabolism and insulin levels during the weight loss plateau phase? 📖 Non-Scale Victories (NSV) — Improvements in energy, sleep, and disease reversal that matter just as much as the numbers on the scale during your tra… ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend: best practices and common mistakes to avoid? ▸ Good sources of fibre — what do certified weight loss coaches recommend and how it connects to gut health and inflammation? ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Diabetics with TPN (IV nutrition experience) and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients — what certified coaches recommend? ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term) on a low-carb or ketogenic diet? ▸ I sometimes feel like people only talk about the obvious symptoms like irregular periods or weight gain, but the fatigue can be just as overwhelming. Has anyone else felt completely drained even: how to talk to your doctor about this: best practices and common mistakes to avoid? 📖 Metabolic Efficiency — The state where your body processes fuel cleanly and maintains high energy levels without the need for constant snacking… ▸ What’s your favorite toothpaste for people with insulin resistance for long-term maintenance (not just short-term)? ▸ What is your immediate go to for some relief during ha — what most people get wrong about this — what certified coaches recommend? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation specifically for women over 40? 📖 Tirzepatide Micro-Dosing — The practice of using the lowest effective dose to achieve results, minimizing side effects while maximizing the longevi… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? ▸ Sugar free 2020, who's with me — what most people get wrong about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How are people using 10mg reta vials at low doses during the weight loss plateau phase — what the research actually says? 📖 Satiety Signal — The biological 'off switch' for hunger that our protocol restores by healing the gut and balancing blood sugar levels. ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend — what certified coaches recommend? ▸ What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ What are your thoughts on just removing wheat and grains, but not rice, corn or oats? Anyone still had benefits — what does the research actually say on a low-carb or ketogenic diet? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and how it connects to gut health and inflammation? ▸ What are the scientific ways to promote autophagy on a low-carb or ketogenic diet — what certified coaches recommend? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide?