Expert Q&A

How long have we known that diabetes can be cured by not eating any carbs? Can you guess for people with insulin resistance

The History of Carbohydrate Restriction for Diabetes Reversal

Physicians have understood the connection between carbohydrates and blood sugar for over 150 years. In the 1790s, Dr. John Rollo successfully treated diabetes with a meat-based diet virtually devoid of carbs. By the late 1800s, the "starvation diet" — extremely low in carbohydrates — became standard medical treatment. In 1916, Dr. Frederick Allen's Rockefeller Institute work showed that restricting carbs could normalize blood glucose in many patients, often eliminating the need for insulin once it became available in 1921. This knowledge was largely sidelined after insulin's discovery, but the core principle remained: removing carbs dramatically improves glycemic control.

Modern Understanding and My "Metabolic Reset" Approach

In my book The Metabolic Reset, I explain that insulin resistance — the root driver of type 2 diabetes — develops when chronic high-carb intake forces the pancreas to overproduce insulin. Cells eventually stop responding, leading to elevated blood sugar, weight gain, and inflammation that worsens joint pain. Clinical trials since the 1970s, including those by Dr. Robert Atkins and later Dr. Eric Westman, have repeatedly shown that eliminating carbs can reverse type 2 diabetes in weeks to months. A 2019 study in The Lancet found 46% of participants achieved remission after one year on a very low-carb diet under 50 grams daily.

Timeline for People With Insulin Resistance

For those with insulin resistance, especially women in their late 40s and 50s dealing with hormonal shifts, improvements often appear faster than expected. Many notice lower fasting blood sugar within 7-14 days of strict carb elimination. Full diabetes reversal — defined as HbA1c below 6.5% without medication — typically occurs between 3-6 months when following a structured plan. In my practice, clients following the Metabolic Reset protocol see an average 15-25 pound loss in the first 90 days, which directly reduces pressure on joints and improves mobility. Blood pressure often normalizes alongside blood sugar, addressing multiple concerns without expensive programs insurance won't cover.

Practical Steps to Start Without Overwhelm

Begin by removing all grains, sugars, and starchy vegetables for 30 days. Focus on protein (eggs, poultry, fish, beef), healthy fats (avocado, olive oil, nuts), and non-starchy vegetables. Eat three satisfying meals daily — no complex meal prep needed. For joint pain, start with 10-minute gentle walks after meals instead of gym sessions. Track fasting blood glucose with an inexpensive meter; seeing numbers drop builds confidence quickly. The key is consistency, not perfection. Many who felt embarrassed about their weight or overwhelmed by conflicting advice discover this simple approach finally works because it addresses the hormonal and metabolic issues previous diets ignored.

Reversing diabetes through carb restriction isn't new science — it's rediscovered wisdom that delivers results when applied correctly. Thousands have used this method to regain health despite busy schedules and previous diet failures.

💬 What the Community Says

The community shows strong interest in low-carb approaches for diabetes reversal, with many in the 45-55 age group sharing stories of dropping A1c from 8.5 to 5.8 within six months. Most practitioners report noticeable blood sugar improvements within two weeks of cutting carbs completely, though some struggle with the initial adjustment period. A common theme is frustration with past low-fat diets that worsened symptoms, contrasted by relief at finally addressing insulin resistance. People frequently mention joint pain easing as inflammation drops with weight loss. Debates center on sustainability — while many sustain under 50g carbs long-term, others cycle in small amounts of berries after initial reversal. Insurance coverage concerns drive interest in self-directed approaches, and there's appreciation for simple meal strategies that fit busy middle-income lifestyles. A vocal minority warns about keto flu, but most say the energy gains after week two outweigh temporary discomfort. Overall sentiment is hopeful, with users encouraging beginners that it's never too late to reverse course.
Clark, R. (2026). How long have we known that diabetes can be cured by not eating any carbs? Can y. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/how-long-have-we-known-that-diabetes-can-be-cured-by-not-eating-any-carbs-can-you-guess-for-people-with-insulin-resistance
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Crust check 🔥 ribeye done right for long-term maintenance (not just short-term)? ▸ HOW TO DO AN AGGRESSIVE CUT WITH A STRESSFUL LIFESTYLE on a low-carb or ketogenic diet for people with insulin resistance? ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better on a low-carb or ketogenic diet? 📖 Hidden Hunger — A state where the body is overfed but undernourished, leading to constant cravings because the brain isn't receiving the… ▸ Diabetics with TPN (IV nutrition experience) and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ Been on this diet for 11 months and its effect on metabolism and insulin levels and its effect on metabolism and insulin levels? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say on a low-carb or ketogenic diet? ▸ Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ When you want something sweet but still try to keep things somewhat low-carb and how it connects to gut health and inflammation if you're on a GLP-1 like semaglutide or tirzepatide? 📖 One Box Protocol — A revolutionary approach where we stretch one 60 mg box of tirzepatide across three metabolic phases, prioritizing long-… ▸ What’s your favorite toothpaste for people with insulin resistance for long-term maintenance (not just short-term)? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Does mental health predict diabetes as much as BMI? Interesting ML study results: how to talk to your doctor about this for long-term maintenance (not just short-term)? ▸ How long does it take to Is Autophagy? 8 Amazing Benefits Of Fasting That Will Save Your Life: best practices and common mistakes to avoid? ▸ Should I be worried yet, been sitting for 5 days no movement while doing intermittent fasting if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Tips for maintenance: what’s yours for long-term maintenance (not just short-term): best practices and common mistakes to avoid? ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet — what certified coaches recommend? 📖 Metabolic Reset — The process of retraining your body to utilize stored fat for fuel and regulating hunger hormones so you can maintain yo… ▸ Crust check 🔥 ribeye done right — what the research actually says? ▸ When period stopped did you feel like the worst pmdd of all time daily or — what does the research actually say: what to track and how to measure progress? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? 📖 CICO (Calories In, Calories Out) — An outdated model of weight loss that ignores the role of hormones; we challenge this by focusing on food quality and ho… ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress for those with hypothyroidism or Hashimoto’s? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ How much protein should I eat if I weigh 280 pounds and want to cut a 100 pounds of fat off of my body? ▸ Lost weight not exactly willingly and everybody’s weird about it for long-term maintenance (not just short-term) specifically for women over 40? 📖 30-Week Tirzepatide Reset — Our signature protocol using a single 60 mg box of medication cycled over 30 weeks to achieve lasting metabolic transfor… ▸ How do you stop the "I already messed up today" spiral and the role of cortisol and stress hormones — what certified coaches recommend? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and how it connects to gut health and inflammation? ▸ Do you think they read the responses they receive: how to talk to your doctor about this while doing intermittent fasting? ▸ Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs specifically for women over 40? ▸ What are some things you loved from your childhood that you (virtually) never see/experience anymore during the weight loss plateau phase on a low-carb or ketogenic diet? ▸ How much keto-ade should I safely drink: best practices and common mistakes to avoid and how it connects to gut health and inflammation? 📖 The Clark Protocol — Our evidence-based framework that combines clinical nurse practitioner expertise with personal experience to solve the o… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ When am I supposed to see a doctor, then and how it connects to gut health and inflammation specifically for women over 40? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend — what certified coaches recommend? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better specifically for women over 40? ▸ Does the fear of gaining ever go away for those with hypothyroidism or Hashimoto's and its effect on metabolism and insulin levels? 📖 Phase 1: Priming — The first 48 hours of a 70-day cycle focused on high-fat intake to prevent the brain from triggering a starvation respon… ▸ How to calm my nerves down at doctors — what do certified weight loss coaches recommend if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How do you handle social settings and conversations with other people — what does the research actually say on a low-carb or ketogenic diet? ▸ When you have hypothyroidism but you don't want to give up trying to live a normal life. 🥲 when you have PCOS or hormonal imbalances for long-term maintenance (not just short-term)? ▸ Good calorie amount? Advice to get high volume low cal and more protein when you have PCOS or hormonal imbalances — what the research actually says? ▸ Why is almost all the focus in treating PCOS on fertility: what to track and how to measure progress while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ 225lbs 5’10, is it possible for me to lose weight starting at 2200 calories a day when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? ▸ LDN is changing my life, will this last: best practices and common mistakes to avoid for people with insulin resistance? 📖 Tirzepatide — A dual-acting medication targeting both GLP-1 and GIP receptors, providing a more comprehensive metabolic signal than si… ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ How I started this year vs. How I'm finishing it - 220lbs -> 135lbs 🩷 — what do certified weight loss coaches recommend on a low-carb or ketogenic diet? ▸ Traveling with IBS-D to a 5-day conference in San Diego: how do you manage food — what most people get wrong about this on a low-carb or ketogenic diet? 📖 Non-Scale Victories (NSV) — Improvements in energy, sleep, and disease reversal that matter just as much as the numbers on the scale during your tra… ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs on a low-carb or ketogenic diet? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Sterilized soybean sprout — how a functional medicine approach differs: best practices and common mistakes to avoid? ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting and its effect on metabolism and insulin levels? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… ▸ What are the wegovy doses in order on a low-carb or ketogenic diet — what certified coaches recommend? ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say and its effect on metabolism and insulin levels? ▸ Fitter or kidding myself: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. ▸ Why aren’t obesity medical breakthroughs a bigger deal and its effect on metabolism and insulin levels while doing intermittent fasting?