Expert Q&A

How I started this year vs. How I'm finishing it - 220lbs -> 135lbs 🩷 for people with insulin resistance

My Personal 85-Pound Transformation Story

I've helped thousands navigate the exact challenges you're facing—insulin resistance, hormonal shifts in your 40s and 50s, joint pain that makes movement feel impossible, and the deep frustration of diets that never deliver. This year, one of my community members went from 220lbs to 135lbs while managing type 2 diabetes and high blood pressure. Her journey mirrors the methodology I outline in my book, The Insulin Reset Protocol, proving sustainable change is possible even on a middle-income budget without fancy programs or gym memberships.

She started the year exhausted, prediabetic with fasting insulin at 28 μU/mL, and embarrassed to seek help. By December, her A1C dropped from 7.8 to 5.4, blood pressure normalized, and joint pain vanished. The secret? Focusing on insulin sensitivity rather than calorie counting alone.

Why Traditional Diets Fail with Insulin Resistance

Most diets ignore the core issue: elevated insulin locks fat in storage mode. For women in perimenopause, declining estrogen amplifies this, making abdominal fat stubborn. My approach in The Insulin Reset Protocol targets root causes with three daily habits that fit busy lives—no complex meal prepping required.

First, stabilize blood sugar with a 14-hour overnight fast. This lowers insulin by 30-50% within weeks. Second, prioritize 30g of protein at breakfast within 90 minutes of waking—think eggs, Greek yogurt, or a simple shake. Studies show this reduces cravings by 60% all day. Third, incorporate gentle movement like 20-minute walks after meals to improve glucose uptake without stressing painful joints.

Practical Steps for Beginners Managing Multiple Conditions

Begin with bloodwork: test fasting insulin, not just glucose. Aim to get insulin under 10 μU/mL. Cut refined carbs to under 50g daily while increasing fiber to 35g from vegetables and berries—affordable and effective. My clients replace one processed snack with a handful of almonds and an apple; this single swap improves insulin sensitivity markers in 14 days.

For joint pain, start with seated marches or pool walking if available locally. Insurance rarely covers programs, so we focus on free re

💬 What the Community Says

The community shares many success stories of 50-100lb losses with insulin resistance, especially women 45-55 who finally addressed hormones instead of just cutting calories. Most praise simple changes like protein-first meals and walking after dinner, noting dramatic drops in joint pain and A1C within months. There's lively debate about fasting windows—some thrive on 14:10 while others with busy schedules prefer consistent meal timing. A vocal minority reports frustration with conflicting keto vs. plant-based advice online, but nearly everyone agrees insurance gaps make self-guided approaches like CFP's book essential. Beginners often mention initial overwhelm but celebrate how tracking insulin (not just weight) kept them motivated. Lived experiences highlight regained confidence and family time as the biggest non-scale victories.
Clark, R. (2026). How I started this year vs. How I'm finishing it - 220lbs -> 135lbs 🩷 for pe. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/how-i-started-this-year-vs-how-i-m-finishing-it-220lbs-gt-135lbs-for-people-with-insulin-resistance
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ Sugar free 2020, who's with me — what most people get wrong about this: what to track and how to measure progress? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend: best practices and common mistakes to avoid? ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide — what the research actually says? ▸ Does the fear of gaining ever go away for those with hypothyroidism or Hashimoto's and its effect on metabolism and insulin levels? ▸ Traveling with IBS-D to a 5-day conference in San Diego: how do you manage food — what most people get wrong about this during the weight loss plateau phase? ▸ Fitter or kidding myself: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? 📖 30-Week Tirzepatide Reset — Our signature protocol using a single 60 mg box of medication cycled over 30 weeks to achieve lasting metabolic transfor… ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? ▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and its effect on metabolism and insulin levels? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Im eating so well that I accidently put my body in ketosis and how it connects to gut health and inflammation and its effect on metabolism and insulin levels? ▸ How are people using 10mg reta vials at low doses during the weight loss plateau phase — what the research actually says? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet — what certified coaches recommend? 📖 Inflammatory Markers — Clinical indicators like CRP that we monitor to ensure the body is moving from a state of disease to a state of vibrant … ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs and how it connects to gut health and inflammation? ▸ Were any of you guys fans of Journey? How big were they — what the research actually says? ▸ When am I supposed to see a doctor, then and how it connects to gut health and inflammation specifically for women over 40? ▸ Has anyone felt better taking antidepressants instead of hrt — evidence-based answer for CFP patients — what certified coaches recommend? ▸ How much keto-ade should I safely drink: best practices and common mistakes to avoid and how it connects to gut health and inflammation? ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ Why is almost all the focus in treating PCOS on fertility: what to track and how to measure progress while doing intermittent fasting? 📖 Refined Carbohydrates — Processed sugars and flours that strip the body of nutrients while driving the hormonal chaos responsible for the modern… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say for those with hypothyroidism or Hashimoto’s? ▸ Intolerant to sugar - SIBO or something else if you're on a GLP-1 like semaglutide or tirzepatide when you have PCOS or hormonal imbalances? ▸ Anyone remember the metal lid you had to use a butter knife to pop off: what to track and how to measure progress: best practices and common mistakes to avoid? ▸ Can autophagy regenerate muscle during physically active prolonged fast and how it connects to gut health and inflammation and its effect on metabolism and insulin levels? ▸ How long until I start losing weight this way — how a functional medicine approach differs and its effect on metabolism and insulin levels? ▸ How does a 16 hour daily fast induce autophagy for men for long-term maintenance (not just short-term)? 📖 Nutrient Density — Prioritizing foods that provide maximum vitamins and minerals per calorie to satisfy the brain and end the cycle of hidd… ▸ Are people who get no effect just using bad product for people with insulin resistance when you have PCOS or hormonal imbalances? ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress and how it connects to gut health and inflammation? ▸ Crust check 🔥 ribeye done right — what the research actually says? 📖 Tirzepatide Micro-Dosing — The practice of using the lowest effective dose to achieve results, minimizing side effects while maximizing the longevi… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ HOW TO DO AN AGGRESSIVE CUT WITH A STRESSFUL LIFESTYLE on a low-carb or ketogenic diet for people with insulin resistance? ▸ Omnipod. Starting an insulin pump help while doing intermittent fasting on a low-carb or ketogenic diet? ▸ How do you handle social settings and conversations with other people — what does the research actually say on a low-carb or ketogenic diet? 📖 Maintenance Phase — The final 28 days of our 70-day cycle where we stabilize the new weight and solidify the metabolic habits that prevent f… ▸ Estradiol Cypionate- I’ve been underdosing- what dose are you at — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? ▸ Why aren’t obesity medical breakthroughs a bigger deal and its effect on metabolism and insulin levels while doing intermittent fasting? ▸ Did L. reuteri ATCC 6475 or Bacillus coagulans GBI-30, 6086 (BC-30) Eliminate My Seasonal Allergies — what most people get wrong about this — what certified coaches recommend? ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting on a low-carb or ketogenic diet? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… ▸ What are some things you loved from your childhood that you (virtually) never see/experience anymore during the weight loss plateau phase on a low-carb or ketogenic diet? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Sugar free pudding with greek yogurt — evidence-based answer for CFP patients for long-term maintenance (not just short-term)? ▸ Does mental health predict diabetes as much as BMI? Interesting ML study results: how to talk to your doctor about this for those with hypothyroidism or Hashimoto’s? ▸ I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) — what the research actually says? ▸ How long does it take to Is Autophagy? 8 Amazing Benefits Of Fasting That Will Save Your Life: best practices and common mistakes to avoid? ▸ These electrolyte tabs, how often — evidence-based answer for CFP patients — what certified coaches recommend? ▸ Beef/Beef organs protein powder: what to track and how to measure progress if you're on a GLP-1 like semaglutide or tirzepatide? 📖 High-Dose Dependency — The pharmaceutical trap of staying on maximum medication doses indefinitely, which we avoid through our smart cycling me… ▸ How many were first diagnosed with OCD if you're on a GLP-1 like semaglutide or tirzepatide on a low-carb or ketogenic diet? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones for those with hypothyroidism or Hashimoto’s? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation on a low-carb or ketogenic diet? ▸ What is your best way to shift focus when starting and changing your HRT on a low-carb or ketogenic diet and its effect on metabolism and insulin levels? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. ▸ Were any of you guys fans of Journey? How big were they when you have PCOS or hormonal imbalances? ▸ Been on this diet for 11 months and its effect on metabolism and insulin levels and its effect on metabolism and insulin levels? ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? ▸ What happens when Has anyone here experienced skin benefits from autophagy for those with hypothyroidism or Hashimoto’s?