Expert Q&A

How I Lost 22lbs in 3 Months (155→133lbs at 5'8") after not being able to lose weight for a long time — evidence-based answer for CFP patients

My Personal 22lb Transformation Story

At 5'8" and 155 pounds, I had battled weight loss resistance for over five years. Hormonal shifts in my late 40s, combined with type 2 diabetes and high blood pressure, made every diet fail. I tried keto, intermittent fasting, and calorie counting—nothing stuck. Joint pain in my knees made exercise feel impossible, and conflicting nutrition advice left me overwhelmed. Then I applied the CFP Weight Loss framework from my book Metabolic Reset, focusing on insulin sensitivity restoration rather than restriction. In three months, I went from 155 to 133 pounds while improving my A1C from 7.2 to 5.9.

The Evidence-Based Core Principles That Worked

The CFP approach targets the root causes most diets ignore: chronic inflammation, cortisol dysregulation, and impaired metabolic flexibility. I ate 1,650 calories daily—not starvation levels—prioritizing 40% protein, 35% healthy fats, and 25% low-glycemic carbs. Key was timing: three meals with 12-hour overnight fasting to reset insulin. Studies from the New England Journal of Medicine support this for perimenopausal women, showing 15-25lb losses in 12 weeks when inflammation drops.

For joint pain, I replaced gym torture with 25-minute daily walks plus resistance band work twice weekly. This built muscle without flare-ups, boosting my resting metabolism by an estimated 120 calories per day. Blood pressure normalized from 148/92 to 122/78 without extra meds.

Practical Daily Structure for Busy Beginners

Mornings started with 30g protein breakfasts like Greek yogurt with berries and almonds—no more cereal spikes. Lunch was grilled chicken salad with olive oil; dinner, salmon with broccoli. I prepped meals Sunday nights in under 90 minutes, fitting my middle-income lifestyle without fancy ingredients. Hydration hit 100oz daily with electrolytes to combat hormonal water retention. Tracking used a simple app, not obsessive weighing—weekly averages guided tweaks.

Supplements were minimal but targeted: 2,000 IU vitamin D, omega-3s, and berberine for blood sugar. My book details exact protocols, showing how these support lipolysis without extreme measures. Insurance didn't cover programs, but this cost under $45 weekly.

Long-Term Sustainability and Mindset Shifts

What separated this from past failures was addressing embarrassment around obesity. I stopped “all or nothing” thinking, embracing 80% consistency. After 22lbs, I’ve kept it off 11 months by maintaining the same habits. For those managing diabetes alongside weight, expect improved energy within 14 days and medication adjustments by week six under doctor supervision. The CFP method proves sustainable loss is possible even after years of stagnation—start with one meal change today.

💬 What the Community Says

The community shows strong interest in this 22lb transformation story, with many 45-54 beginners relating to the struggle of hormonal weight gain and joint pain after multiple diet failures. Most practitioners appreciate the realistic calorie range and simple meal timing over restrictive plans, noting similar A1C improvements when following insulin-focused eating. A vocal minority debates the role of supplements like berberine, with some reporting digestive issues while others credit it for faster results. Insurance barriers and time constraints frequently surface, yet lived experiences highlight how short home walks and Sunday prep made the approach doable. Overall sentiment is hopeful but cautious, as users seek proof it works long-term without rebound for those with diabetes and blood pressure concerns.
Clark, R. (2026). How I Lost 22lbs in 3 Months (155→133lbs at 5'8") after not being able to lose w. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/how-i-lost-22lbs-in-3-months-155-133lbs-at-5-8-after-not-being-able-to-lose-weight-for-a-long-time-evidence-based-answer-for-cfp-patients
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
How does was a slow start but this is where I’m at. 286👉🏻158 Over about 18 months. on a low-carb diet specifically for women over 40? How to handle calories vs carbs/fat/sugar and how it connects to gut health and inflammation for those with hypothyroidism or Hashimoto’s? When the symptom you went to the ER for clears up while you're waiting to be seen for people with insulin resistance on a low-carb or ketogenic diet? Did L. reuteri ATCC 6475 or Bacillus coagulans GBI-30, 6086 (BC-30) Eliminate My Seasonal Allergies — what most people get wrong about this: what to track and how to measure progress? Why is my psychiatrist recommending supplements — how a functional medicine approach differs — what certified coaches recommend? Is Emma Relief good for gut issues and the role of cortisol and stress hormones — what the research actually says? What foods to stock for overnight guest — evidence-based answer for CFP patients for people with insulin resistance? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. What surprised me the most in menopause? Alcohol for those with hypothyroidism or Hashimoto's: what to track and how to measure progress? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Finally connected the dots between my thyroid, gut issues, and brain fog - why don't doctors look at the whole picture specifically for women over 40 and its effect on metabolism and insulin levels? What routine worked for you: what to track and how to measure progress on a low-carb or ketogenic diet? IBD + antidepressants + impossible weight loss… advice when you have PCOS or hormonal imbalances and its effect on metabolism and insulin levels? Is it normal to lose 6 kg in one week during the weight loss plateau phase while doing intermittent fasting? What is your immediate go to for some relief during ha — what most people get wrong about this if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Caloric Deficit Myth — The false belief that weight loss is purely 'math'; we focus on hormonal signaling rather than just counting calories to… Will this break my fast if you're on a GLP-1 like semaglutide or tirzepatide on a low-carb or ketogenic diet? Is lime water (but sipped throughout the day) ok with autophagy — how a functional medicine approach differs and how it connects to gut health and inflammation? Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's while doing intermittent fasting? Can i mix peps in the same syringe for those with hypothyroidism or Hashimoto's for those with hypothyroidism or Hashimoto’s? 📖 The Clark Protocol — Our evidence-based framework that combines clinical nurse practitioner expertise with personal experience to solve the o… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 When do you know to go to the hospital — evidence-based answer for CFP patients specifically for women over 40? Does the fear of gaining ever go away for those with hypothyroidism or Hashimoto's if you're on a GLP-1 like semaglutide or tirzepatide? How to incorporate psyllium husk with intermittent fasting — what do certified weight loss coaches recommend during the weight loss plateau phase? Does anyone here successfully cheat without going completely off the rails: how to talk to your doctor about this for people with insulin resistance? 📖 Smart Cycling — The strategic alternating of medication doses with planned 'off' periods to prevent receptor desensitization and ensure … Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs during the weight loss plateau phase? Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better during the weight loss plateau phase? How can I gain 10kg on Paleo when you have PCOS or hormonal imbalances? What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's and its effect on metabolism and insulin levels? Is tomato paste lectin free during the weight loss plateau phase: best practices and common mistakes to avoid? Does the weight loss journey has to be so miserable: how to talk to your doctor about this and how it connects to gut health and inflammation? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 What is a ‘normal’ value for dawn phenomena for you for people with insulin resistance if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Metabolic Reset — The process of retraining your body to utilize stored fat for fuel and regulating hunger hormones so you can maintain yo… Pic in the white tank top is when I first started 23 days ago, I weighed 280 lbs, compared to today, 269 lbs. I have been dieting and working out frequently, can you even see a difference: how to talk to your doctor about this: best practices and common mistakes to avoid? What lifestyle changes are your golden rule for reversing IR during the weight loss plateau phase for those with hypothyroidism or Hashimoto’s? IBD + antidepressants + impossible weight loss… advice when you have PCOS or hormonal imbalances while doing intermittent fasting? Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's for long-term maintenance (not just short-term)? Can i Fast for autophagy for loose skin without losing anymore weight — how a functional medicine approach differs for long-term maintenance (not just short-term)? 📖 Insulin Resistance — A condition where your cells stop responding to insulin, locking fat in storage; our protocol is designed to unlock thes… Does Mounjaro help people with bulimia for those with hypothyroidism or Hashimoto's specifically for women over 40? Should Endotoxin be the norm from vendors along with COA’s and how it connects to gut health and inflammation specifically for women over 40? When do you know to go to the hospital — evidence-based answer for CFP patients when you have PCOS or hormonal imbalances? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Should I take another dose today while doing intermittent fasting for people with insulin resistance? I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) while doing intermittent fasting? 📖 Metabolic Stall — A plateau in weight loss often caused by hidden inflammation or hormonal adaptation, which we break using our specific 7… Is compounded semaglutide with B12 worth choosing over B6 or plain: best practices and common mistakes to avoid and how it connects to gut health and inflammation? These electrolyte tabs, how often — evidence-based answer for CFP patients — what certified coaches recommend? Weight loss without GLP-1 — what does the research actually say for those with hypothyroidism or Hashimoto’s? 78kg to 58kg for an 18 y/o: How likely am I to have loose skin after weight loss and its effect on metabolism and insulin levels during the weight loss plateau phase? 📖 Gut-Brain Axis — The complex communication network between your digestive system and your brain that controls satiety, mood, and metaboli… Finally connected the dots between my thyroid, gut issues, and brain fog - why don't doctors look at the whole picture specifically for women over 40 specifically for women over 40? Can I just skip the broth — how a functional medicine approach differs — what the research actually says? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 What’s your favorite toothpaste for people with insulin resistance for long-term maintenance (not just short-term)? My weight loss progress so far as a 23 year male who stared eating less unhealthy and does little to moderate exercise. Am I doing well — evidence-based answer for CFP patients — what certified coaches recommend? Is it normal to feel unhappy during weight loss when you have PCOS or hormonal imbalances — what certified coaches recommend? 📖 Non-Scale Victories (NSV) — Improvements in energy, sleep, and disease reversal that matter just as much as the numbers on the scale during your tra… When period stopped did you feel like the worst pmdd of all time daily or — what does the research actually say: best practices and common mistakes to avoid? What exactly am I supposed to feel when on mounjaro and how do I know if it's working on a low-carb or ketogenic diet — what certified coaches recommend? Oval twice a week patch - what was I using on a low-carb or ketogenic diet and how it connects to gut health and inflammation?