Expert Q&A

Has anyone with loose skin tried water fasting for long periods of time? and hie did it effect the loose skin and its effect on metabolism and insulin levels

Understanding Water Fasting in Midlife Weight Loss

As the founder of CFP Weight Loss and author of The Metabolic Reset Protocol, I've guided thousands through sustainable approaches, especially those in their 40s and 50s facing hormonal changes that make shedding pounds feel impossible. Water fasting—consuming only water for extended periods, typically 3-21 days—has gained attention for rapid fat loss. However, for complete beginners with joint pain, diabetes, or prior diet failures, it's rarely the first choice due to its intensity and potential risks.

How Water Fasting Affects Loose Skin

Loose skin often appears after significant weight loss when skin elasticity diminishes with age, rapid loss, or nutrient gaps. In my experience, prolonged water fasting can worsen loose skin initially because it accelerates fat reduction without building supportive muscle or collagen. Without protein intake, the body may break down lean tissue, reducing skin firmness. Some report modest improvement over months as autophagy (cellular cleanup) kicks in around day 3-5, potentially aiding skin remodeling. Yet, most see better results combining shorter fasts with resistance exercises that fit busy schedules—think 20-minute home sessions to avoid joint strain. Hydration during fasting helps skin plumpness, but don't expect miracles without follow-up collagen support from bone broth post-fast.

Impact on Metabolism and Insulin Levels

Water fasting powerfully resets insulin levels. Studies show insulin drops 50-70% within 24-48 hours as the body shifts to burning fat, improving sensitivity crucial for those managing blood pressure and diabetes. This can break through hormonal weight loss resistance. However, metabolism often slows by 10-20% after 72 hours due to metabolic adaptation, a protective response that conserves energy—exactly why many regain weight post-diet. In The Metabolic Reset Protocol, I emphasize cycling shorter 16-24 hour fasts with nutrient-dense refeeds to prevent this slowdown. Electrolyte balance (sodium, potassium, magnesium) is non-negotiable to avoid fatigue, especially on middle-income budgets without insurance-covered programs.

Practical Guidance for Beginners

Start small: try 24-48 hour water fasts under medical supervision if you have diabetes or blood pressure issues. Focus on rebuilding with strength training 2-3 times weekly to firm skin and boost metabolism by up to 15%. Track progress with measurements over scale weight. My method prioritizes simple, time-efficient meal plans using affordable whole foods to combat overwhelming nutrition advice. Most see sustainable 1-2 pounds weekly loss without embarrassment or complex prep. Consult your doctor before extended fasts to ensure safety with your health profile.

💬 What the Community Says

In online forums like Reddit's r/fasting and r/LooseSkin, users in their late 40s and early 50s share mixed experiences with extended water fasting. Many report noticeable improvements in insulin sensitivity and easier blood sugar control, especially those dealing with type 2 diabetes, but complain of worsened loose skin appearance during the fast due to rapid fat loss. A common theme is initial metabolic slowdown leading to plateaus, with several noting they felt colder and more fatigued after day 5. The community is split on long-term benefits: some praise autophagy for skin tightening over 6+ months when combined with strength training, while others warn of muscle loss making joint pain worse. Beginners often express hesitation about trying it without medical oversight, citing past diet failures and lack of insurance support. Most agree shorter intermittent fasting feels more sustainable for busy schedules than multi-week water fasts.
Clark, R. (2026). Has anyone with loose skin tried water fasting for long periods of time? and hie. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/has-anyone-with-loose-skin-tried-water-fasting-for-long-periods-of-time-and-hie-did-it-effect-the-loose-skin-and-its-effect-on-metabolism-and-insulin-levels
Russell Clark, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Have a follow-up question?
More Questions 200 answered
What's a good Soy Sauce alternative for Asian Cuisine — what does the research actually say? What tissues show the biggest metabolic remodeling in z2: best practices and common mistakes to avoid Is it even worth it anymore: best practices and common mistakes to avoid Insomnia while taking oral minoxidril if you're on a GLP-1 like semaglutide or tirzepatide Any suggestions for staying on the program while traveling and how it connects to gut health and inflammation 📖 Metabolic Stall — A plateau in weight loss often caused by hidden inflammation or hormonal adaptation, which we break using our specific 7… Any women here that never had a flat stomach in their lives during the weight loss plateau phase How it goes trying to dose insulin every day: how to talk to your doctor about this Do you avoid socialising or seeing family because of how tired you are and how much effort it is to be in company while doing intermittent fasting What actually helped my Hashimoto's symptoms — food changes that made a difference for me for those with hypothyroidism or Hashimoto's Le mounjaro peut il se conserver au frigo if you're on a GLP-1 like semaglutide or tirzepatide 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → E Patch to Injections how long did you leave your patch on: what to track and how to measure progress How do you gauge progress from zone 2 — what does the research actually say? 📖 CICO (Calories In, Calories Out) — An outdated model of weight loss that ignores the role of hormones; we challenge this by focusing on food quality and ho… Can we talk about the founder for those with hypothyroidism or Hashimoto's Le mounjaro peut il se conserver au frigo — what do certified weight loss coaches recommend? What about oxalates — how a functional medicine approach differs One avocado a day? What's up with that? Does anyone remember if the good doctor ever gave us an explanation for that: how to talk to your doctor about this Hitting protein goals. How do you do it and how it connects to gut health and inflammation 📖 Metabolic Efficiency — The state where your body processes fuel cleanly and maintains high energy levels without the need for constant snacking… How I found out I had uterine cancer, what I wish I had known, and what everyone with PCOS should know about their period if you're on a GLP-1 like semaglutide or tirzepatide 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → How it looks when you lose 170 lbs. but are still a fat man — what most people get wrong about this What a month of paleo has done for me while doing intermittent fasting Can’t stand avocados or guacamole. Help — what most people get wrong about this Anyone else with hashimoto's AND adhd in here during the weight loss plateau phase Here's the things I wish I'd known back then... what are yours — what do certified weight loss coaches recommend? PCOS linked to childhood trauma if you're on a GLP-1 like semaglutide or tirzepatide 📖 Rebound Weight Gain — The common 'yo-yo' effect caused by high-dose, continuous GLP-1 use; we prevent this through strategic cycling and metab… What is this new frozen hell specifically for women over 40 Can I get an upvote for the true enemy of diabetes while doing intermittent fasting Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why: how to talk to your doctor about this Did my hashimoto cause this for those with hypothyroidism or Hashimoto's 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Ischias oder Piriformus Probleme and how it connects to gut health and inflammation Hitting protein goals. How do you do it — how a functional medicine approach differs App that can predict symptoms before they get bad — how a functional medicine approach differs 📖 Weight Set Point — The internal 'thermostat' for body weight that we aim to lower permanently through our 30-week metabolic reset. Has anyone been diagnosed with Hashimotos after going through emotional distress or chronic stress in general: best practices and common mistakes to avoid Insomnia while taking oral minoxidril while doing intermittent fasting When period stopped did you feel like the worst pmdd of all time daily or on a low-carb or ketogenic diet Can’t stand avocados or guacamole. Help when you have PCOS or hormonal imbalances What a 55 water fast did for me: what to track and how to measure progress Guys, did you know the POWER of exercise for your body for those with hypothyroidism or Hashimoto's When people ask how I can tell my sugar's low and the role of cortisol and stress hormones 📖 Leptin Sensitivity — Restoring your brain's ability to hear the 'I am full' signal, which is often muted by high-sugar diets and systemic inf… 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → How much are people paying for Estring during the weight loss plateau phase How long did you carry a pad post-menopause and how it connects to gut health and inflammation How much are people paying for Estring: how to talk to your doctor about this Anyone stopped responding to Mounjaro and had better results with retatrutide and the role of cortisol and stress hormones How much are people paying for Estring for those with hypothyroidism or Hashimoto's 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… Can we stop posting good glucose levels and pretending they are bad — what does the research actually say? Is it just me or is Hashimoto’s greatly underrepresented — what most people get wrong about this How To Speed Up Your Metabolism After 40 during the weight loss plateau phase So if you're spacing out your shots - what are y'all doing with extra injectors: how to talk to your doctor about this 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → How does smoking affect GERD while taking tirzepatide? Is this normal? Feels like a waste: what to track and how to measure progress 📖 Adipose Tissue Signaling — The way fat cells communicate with the brain; our goal is to fix these signals so the body stops defending an unnaturall… What a 55 water fast did for me while doing intermittent fasting