Expert Q&A

Does this look like Insulin Resistance?

The Visible and Invisible Red Flags

When you feel like you’re doing everything right—meticulously tracking calories and staying active—but the scale remains frozen, your body is likely struggling with Hyperinsulinemia. This is a physiological state where your pancreas overproduces insulin to keep blood sugar stable because your cells have stopped responding to the hormone. One of the most common physical markers I look for in my practice is Acanthosis Nigricans, which manifests as darkened, velvety patches of skin typically found around the neck, armpits, or groin. If you are also noticing a sudden proliferation of small skin tags or a stubborn increase in Visceral Adiposity (the firm fat stored deep in the abdominal cavity), these are classic indicators that your metabolic machinery is stalling.

The Energy Rollercoaster and 'Hangry' Cycles

For many in the 45-54 age bracket, hormonal shifts like perimenopause or declining testosterone can exacerbate these issues. Do you experience Postprandial Somnolence—that overwhelming urge to nap 30 to 60 minutes after a high-carb meal? Or perhaps you deal with intense "hanger" that makes you feel shaky, irritable, or lightheaded if a meal is delayed by even an hour. These aren't character flaws or a lack of willpower; they are metabolic cries for help. When your cells resist insulin, glucose stays trapped in the bloodstream instead of fueling your muscles, leaving you chronically exhausted while your body remains in a continuous state of fat storage.

Why Your 'Normal' Labs Might Be Lying

A common frustration I hear from beginners is, "My doctor says my labs are normal, so why do I feel so bad?" Standard blood tests often only look at Fasting Plasma Glucose or A1c. However, these are "lagging" indicators. By the time your blood sugar is high enough to be flagged, insulin resistance has often been present for a decade. To get a real answer, I recommend calculating your HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) score. This requires testing your fasting insulin alongside your glucose. A high insulin level, even with "normal" blood sugar, confirms your body is working overtime to maintain the status quo, which effectively halts weight loss and drives up blood pressure.

Breaking the Cycle Without the Gym

If joint pain makes traditional exercise feel impossible, do not lose heart. In my methodology at CFP Weight Loss, we emphasize that metabolic flexibility starts in the kitchen, not on the treadmill. Prioritizing high-quality protein and fiber-rich vegetables can stabilize blood sugar and reduce the total insulin load on your system. Simple, low-impact movements like short walks after meals can significantly improve insulin sensitivity without stressing your joints. Addressing these underlying hormonal hurdles is the only way to move past the "failed diet" cycle and achieve the lasting health you deserve.

💬 What the Community Says

The community of individuals struggling with weight loss often expresses deep frustration regarding 'normal' lab results received from primary care physicians despite showing clear symptoms of metabolic dysfunction. Many forum members share photos of skin changes or describe the 'carb coma' that follows lunch, seeking validation that their struggles are physiological rather than a lack of willpower. A significant portion of the community has moved toward self-advocacy, frequently discussing how to order their own fasting insulin tests through private labs when insurance refuses to cover the screening. There is a palpable sense of exhaustion among those in the 45-54 age range, who often feel that hormonal changes and weight gain are dismissed by professionals as 'just getting older.' While some debate the efficacy of specific diets like keto versus low-carb, the consensus remains that stubborn midsection weight is the primary motivator for investigating insulin resistance. The collective sentiment is one of cautious hope mixed with skepticism toward traditional medical advice that ignores the role of insulin in fat storage.
Clark, R. (2026). Does this look like Insulin Resistance?. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/does-this-look-like-insulin-resistance
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
Will doing omad 2-3 times a week get rid of it or reduce loose skin? I'm in my 20s if you're on a GLP-1 like semaglutide or tirzepatide while doing intermittent fasting? How the heck do people with health anxiety handle anxiety med side effects: what to track and how to measure progress — what the research actually says? Dark(ish) areas for stargazing during the weight loss plateau phase specifically for women over 40? Anybody else feel like this — what does the research actually say and its effect on metabolism and insulin levels? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. Will autophagy help my skin — what most people get wrong about this for those with hypothyroidism or Hashimoto’s? Does anyone else remember the darkest time of our Generation — evidence-based answer for CFP patients when you have PCOS or hormonal imbalances? I’m looking into possibly going grain free and I was wondering if it was just as healthy as doing keto or paleo — what most people get wrong about this and how it connects to gut health and inflammation? 📖 Autophagy — The body's natural 'housecleaning' process that occurs during fasting or low-insulin states, promoted during our mainten… Paleo brownies/sweets that ship all over usa: how to talk to your doctor about this while doing intermittent fasting? For those who took metformin, how soon did you see benefits: best practices and common mistakes to avoid during the weight loss plateau phase? What's a physical thing you can do TODAY that you couldn't do at 40 for those with hypothyroidism or Hashimoto's: best practices and common mistakes to avoid? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Can you take beta blockers and GLP-1s together: best practices and common mistakes to avoid and its effect on metabolism and insulin levels? How I cured my bad breath. Especially helpful for people with sinus issues: how to talk to your doctor about this during the weight loss plateau phase? Anybody else wake up after 5-6 hours because their lower back starts hurting — what does the research actually say for long-term maintenance (not just short-term)? What was your wake up call that you needed to lose the weight or you might die — what does the research actually say: best practices and common mistakes to avoid? 📖 Inflammatory Markers — Clinical indicators like CRP that we monitor to ensure the body is moving from a state of disease to a state of vibrant … I lost 100#s using cutting calories and exercising, 10 to 15,000 steps, and I soon plateaued and I was so hungry. After losing weight, does it feel like you could do anything — evidence-based answer for CFP patients — what certified coaches recommend? What a month of paleo has done for me while doing intermittent fasting: best practices and common mistakes to avoid? Any Links Between Autophagy & Eye Disease Reversing when you have PCOS or hormonal imbalances for people with insulin resistance? Anybody else wake up after 5-6 hours because their lower back starts hurting if you're on a GLP-1 like semaglutide or tirzepatide and how it connects to gut health and inflammation? Why are peptides suddenly everywhere in 2026 when most of them have been around for 20 or 30 years — what do certified weight loss coaches recommend specifically for women over 40? 📖 Metabolic Reset — The process of retraining your body to utilize stored fat for fuel and regulating hunger hormones so you can maintain yo… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm — what does the research actually say for people with insulin resistance? After losing weight, does it feel like you could do anything — evidence-based answer for CFP patients if you're on a GLP-1 like semaglutide or tirzepatide? Any of you low carb, low to no fruits people go camping? Even if not, what are you eating and how it connects to gut health and inflammation while doing intermittent fasting? How Much Does 200g Apple Raise Blood Sugar when you have PCOS or hormonal imbalances and its effect on metabolism and insulin levels? Anybody else wake up after 5-6 hours because their lower back starts hurting — what does the research actually say and how it connects to gut health and inflammation? How does this affect is everyone else able to eat normally but I can't if you're on a GLP-1 like semaglutide or tirzepatide? What's a physical thing you can do TODAY that you couldn't do at 40 for those with hypothyroidism or Hashimoto's on a low-carb or ketogenic diet? 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… So a lack of thyroid right while doing intermittent fasting when you have PCOS or hormonal imbalances? Is there such a thing as eating too much fish fat for weight loss — what do certified weight loss coaches recommend while doing intermittent fasting? How I cured my bad breath. Especially helpful for people with sinus issues: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 What to expect on 50mg of Spironolactone for long-term maintenance (not just short-term) and how it connects to gut health and inflammation? After losing weight, does it feel like you could do anything — evidence-based answer for CFP patients when you have PCOS or hormonal imbalances? How did I not get a heads up? I now make it my goal to help, support and inform others heading towards menooause and its effect on metabolism and insulin levels — what certified coaches recommend? 📖 Tirzepatide — A dual-acting medication targeting both GLP-1 and GIP receptors, providing a more comprehensive metabolic signal than si… My friends stopped being impressed by my weight loss ages ago. I just reached my goal weight, would you cheer for me in their place: what to track and how to measure progress when you have PCOS or hormonal imbalances? Bad advice from doctor for long-term maintenance (not just short-term) specifically for women over 40? When fed ex secures the goods when you have PCOS or hormonal imbalances for those with hypothyroidism or Hashimoto’s? Not a whingeing post. Just looking for some guidance.. I started IF with great success. I felt energised & found making note of the fasting stages really motivational. I had a break from IF: how to talk to your doctor about this for people with insulin resistance? One Medical for Lilly Direct on a low-carb or ketogenic diet during the weight loss plateau phase? How did you stop your health anxiety — what do certified weight loss coaches recommend on a low-carb or ketogenic diet? 📖 One Box Protocol — A revolutionary approach where we stretch one 60 mg box of tirzepatide across three metabolic phases, prioritizing long-… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 “You shouldn’t feel anything” while doing intermittent fasting when you have PCOS or hormonal imbalances? Paleo brownies/sweets that ship all over usa: how to talk to your doctor about this for long-term maintenance (not just short-term)? Has anyone with loose skin tried water fasting for long periods of time? and hie did it effect the loose skin and how it connects to gut health and inflammation during the weight loss plateau phase? 📖 Insulin Resistance — A condition where your cells stop responding to insulin, locking fat in storage; our protocol is designed to unlock thes… Do you know of any snacks that you can just chew on when you're bored on a low-carb or ketogenic diet if you're on a GLP-1 like semaglutide or tirzepatide? What is the connection between I reduced my IR from 15.5 to 4 in 3 months when you have PCOS or hormonal imbalances? Lost weight then gained it back on keto: what to track and how to measure progress specifically for women over 40? 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… Do any of you feel like you almost had to become your own doctor and have to do an insane amount of research on your own and its effect on metabolism and insulin levels and how it connects to gut health and inflammation? When I want to lose weight fast I fast while doing intermittent fasting? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Is there such a thing as eating too much fish fat for weight loss — what do certified weight loss coaches recommend on a low-carb or ketogenic diet? Do you follow the food order recommendation for those with hypothyroidism or Hashimoto’s? How I cured my bad breath. Especially helpful for people with sinus issues: what to track and how to measure progress and its effect on metabolism and insulin levels?