Expert Q&A

Do you think privatisation has negatively impact our research capabilities - especially looking at AMR and antibiotic development?

The Privatization Shift in Antibiotic Development

I’ve spent decades examining how systemic changes affect public health, particularly for adults aged 45-54 struggling with hormonal changes, joint pain, and metabolic conditions like diabetes. Privatization of pharmaceutical research has indeed slowed progress against antimicrobial resistance (AMR). Since the 1980s, major drug companies shifted focus to chronic therapies yielding higher returns—statins, diabetes medications, and weight-loss drugs—rather than antibiotics that patients use for only 7-14 days. This economic reality left a void: only 12 new antibiotics reached approval between 2010 and 2020, compared to dozens in prior decades.

Direct Effects on AMR Research Capabilities

Public funding for basic AMR science dropped as private capital dominated. Universities now rely on industry grants, steering research toward patentable compounds instead of broad-spectrum or novel mechanisms. The result? We face “superbugs” resistant to last-line treatments, complicating surgeries, chemotherapy, and even routine infections. For our middle-income readers managing blood pressure and obesity, this matters deeply—an untreated resistant infection can derail any weight loss effort. In my book, I detail how unresolved inflammation from recurrent infections exacerbates insulin resistance, making fat loss 30-40% harder during perimenopause and andropause.

Linking AMR Challenges to Metabolic and Weight Health

Repeated antibiotic courses disrupt the gut microbiome, directly impacting weight. Studies show a single course can shift bacterial populations for up to two years, increasing calorie harvest from food by 10-15%. This is why so many in our community feel they “failed every diet.” My CFP Weight Loss methodology prioritizes microbiome restoration alongside gentle movement that respects joint pain. We recommend 20-minute daily walks, resistance bands at home, and fiber-rich meal plans requiring under 30 minutes prep—practical solutions insurance rarely covers.

Actionable Steps You Can Take Today

While awaiting policy changes, protect yourself. Rotate between fermented foods and targeted prebiotics to rebuild diversity. Track blood glucose responses to meals using affordable monitors. Choose meats raised without routine antibiotics. Most importantly, focus on sustainable fat loss that reduces chronic inflammation, lowering infection risk. My approach has helped thousands reduce HbA1c by 1.5 points while losing 25-40 pounds without extreme measures. Small, consistent habits beat complex plans every time. Start with one change this week—your joints and metabolism will thank you.

💬 What the Community Says

Forum participants express deep concern that privatization has starved antibiotic innovation, with many sharing stories of family members facing resistant infections after years on multiple courses. Most agree big pharma prioritizes profitable chronic drugs over AMR solutions, leaving public research underfunded. A vocal minority points to successful public-private partnerships like CARB-X as hopeful signs, yet skepticism remains high. Middle-aged users frequently connect gut damage from antibiotics to stalled weight loss, hormonal issues, and rising diabetes rates. Many feel overwhelmed by conflicting nutrition advice and embarrassed to discuss obesity-related complications with doctors. There is broad consensus that practical, low-cost lifestyle changes respecting joint pain are more realistic than waiting for new miracle drugs. Insurance limitations and time constraints dominate conversations, with users seeking simple routines that fit real lives rather than theoretical overhauls.
Cite this answer
Clark, R. (2026). Do you think privatisation has negatively impact our research capabilities - esp. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/do-you-think-privatisation-has-negatively-impact-our-research-capabilities-especially-looking-at-amr-and-antibiotic-development
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

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