Expert Q&A

Been a bit up and down the last couple weeks but still another 0.9lbs gone, 33.2lbs total if you're on a GLP-1 like semaglutide or tirzepatide

Celebrating Consistent Progress on Your GLP-1 Journey

Reaching 33.2 pounds lost while using medications like semaglutide or tirzepatide is a meaningful milestone, especially when life feels up and down. That additional 0.9 pounds this week shows your body is still responding, even if the scale isn't dropping dramatically every single day. In my experience helping thousands through the CFP Weight Loss method, these smaller weekly wins add up to sustainable transformation when paired with smart habits that address hormonal changes and metabolic adaptation.

Understanding Normal Fluctuations on Semaglutide and Tirzepatide

GLP-1 medications work by mimicking hormones that regulate appetite and blood sugar, which explains why many in their mid-40s to mid-50s see improved diabetes and blood pressure numbers alongside weight loss. However, water retention, stress, and monthly hormonal shifts can cause the scale to bounce. A 0.9lb loss after inconsistent weeks is actually a positive sign your body is shedding fat steadily. Focus on non-scale victories like looser clothing, better joint comfort during movement, and stable energy levels. My book outlines how tracking waist measurements and energy rather than daily weigh-ins prevents the discouragement that derails most people who've failed previous diets.

Practical Strategies to Maintain Momentum Without Overwhelm

With busy schedules and joint pain making intense exercise difficult, prioritize simple movement: 15-minute walks after meals can enhance tirzepatide's effects on blood sugar without stressing your joints. For nutrition, my approach emphasizes protein-first meals (aim for 25-30g per sitting) using affordable ingredients—no complex plans required. This combats the muscle loss sometimes seen with GLP-1s and supports metabolic rate. If insurance doesn't cover your program, focus on three consistent actions daily: hit your protein target, drink 80-100oz of water, and get 7 hours of sleep. These amplify medication results while addressing the hormonal barriers common in this age group. When embarrassment about obesity creeps in, remember progress like 33.2lbs proves you're already moving forward.

Long-Term Mindset for Sustainable Results Beyond 33lbs

Many reach this stage and worry about plateaus. The CFP method teaches adjusting portion awareness and strength-building moves (using household items) to preserve muscle, which keeps your metabolism active. Those managing blood pressure and diabetes often report needing less medication as weight drops—always coordinate with your doctor. Stay consistent even during up-and-down weeks; the average sustainable loss on these medications with lifestyle support is 1-2lbs weekly after the initial phase. You've already overcome the distrust from past failed diets by showing up for 33.2lbs. Keep that momentum by focusing on how you feel, not just the number. Small, repeatable actions create the lasting change insurance plans often overlook.

💬 What the Community Says

Users tracking GLP-1 medications like semaglutide and tirzepatide frequently share similar experiences of fluctuating weekly losses around 0.5-2lbs, with many celebrating totals near 30-40lbs after several months. The community notes that "up and down" weeks are extremely common, often linked to stress, menstrual cycles, or sodium intake, yet most report the overall trend remains downward. A vocal group debates whether slower losses indicate muscle loss or simply the body's adjustment period, with some recommending weekly measurements over daily scale checks. Beginners in the 45-55 range appreciate posts highlighting joint pain improvements and better blood sugar control, though frustration surfaces around insurance coverage gaps and conflicting online advice. Lived experiences emphasize that non-scale victories like increased energy and clothing fit keep motivation high when the scale stalls. Many echo the sentiment that consistency through plateaus leads to continued progress, with several mentioning they've maintained losses better by pairing meds with simple protein-focused eating rather than restrictive diets.
Clark, R. (2026). Been a bit up and down the last couple weeks but still another 0.9lbs gone, 33.2. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/been-a-bit-up-and-down-the-last-couple-weeks-but-still-another-0-9lbs-gone-33-2lbs-total-if-you-re-on-a-glp-1-like-semaglutide-or-tirzepatide
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
▸ What is the connection between Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better and how it connects to gut health and inflammation? ▸ Has anyone here made their own custom CGM patches with a Cricut for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this — what the research actually says? 📖 Diabetes Reversal — The clinical goal of restoring normal blood sugar levels and insulin function, as seen in patients like John who no long… ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend — what certified coaches recommend? ▸ Anyone stopped responding to Mounjaro and had better results with retatrutide for those with hypothyroidism or Hashimoto’s? ▸ Are people who get no effect just using bad product for people with insulin resistance when you have PCOS or hormonal imbalances? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet when you have PCOS or hormonal imbalances? ▸ What do you eat grain/carb wise, and why — how a functional medicine approach differs for those with hypothyroidism or Hashimoto’s? 📖 The Clark Protocol — Our evidence-based framework that combines clinical nurse practitioner expertise with personal experience to solve the o… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ My weight loss progress so far as a 23 year male who stared eating less unhealthy and does little to moderate exercise. Am I doing well — evidence-based answer for CFP patients for people with insulin resistance? ▸ Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide — what certified coaches recommend? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones on a low-carb or ketogenic diet? ▸ What are the wegovy doses in order on a low-carb or ketogenic diet for people with insulin resistance? ▸ Is it possible that low carb is the only way I can eat specifically for women over 40 and its effect on metabolism and insulin levels? 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. ▸ When do you know to go to the hospital specifically for women over 40? ▸ How much keto-ade should I safely drink: best practices and common mistakes to avoid and how it connects to gut health and inflammation? ▸ How do you handle social settings and conversations with other people — what does the research actually say on a low-carb or ketogenic diet? 📖 Hidden Hunger — A state where the body is overfed but undernourished, leading to constant cravings because the brain isn't receiving the… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Exercise — when and what kind while fasting, and does it enhance autophagy — how a functional medicine approach differs and its effect on metabolism and insulin levels? ▸ Omnipod. Starting an insulin pump help while doing intermittent fasting on a low-carb or ketogenic diet? ▸ Will eating meintenance calories make me lose weight for those with hypothyroidism or Hashimoto's when you have PCOS or hormonal imbalances? ▸ Thyroid tests all in range— but high calcium — how a functional medicine approach differs during the weight loss plateau phase? ▸ If a random dance partner app existed .. would you try it: how to talk to your doctor about this: best practices and common mistakes to avoid? ▸ Low TSH, Low T4, and Low T3 simultaneously on Levothyroxine — anyone experienced this and the role of cortisol and stress hormones — what certified coaches recommend? ▸ Does okra water actually help gut issues: what to track and how to measure progress — what certified coaches recommend? 📖 Maintenance Phase — The final 28 days of our 70-day cycle where we stabilize the new weight and solidify the metabolic habits that prevent f… ▸ What to do if you have to eat late dinners?? How to process the dinner quicker so I'm not burping all night long while doing intermittent fasting: what to track and how to measure progress? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Crust check 🔥 ribeye done right — what the research actually says? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say on a low-carb or ketogenic diet? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances when you have PCOS or hormonal imbalances? ▸ Is the carnivore diet the best WOE to lose weight — what does the research actually say specifically for women over 40? ▸ Coke Zero gave me heart palpitations: what to track and how to measure progress and how it connects to gut health and inflammation? ▸ Crust check 🔥 ribeye done right for long-term maintenance (not just short-term)? 📖 30-Week Tirzepatide Reset — Our signature protocol using a single 60 mg box of medication cycled over 30 weeks to achieve lasting metabolic transfor… ▸ How does a 16 hour daily fast induce autophagy for men for long-term maintenance (not just short-term)? ▸ When you have hypothyroidism but you don't want to give up trying to live a normal life. 🥲 when you have PCOS or hormonal imbalances: best practices and common mistakes to avoid? ▸ How does chasing skinny ever get old for long-term results while doing intermittent fasting? ▸ Traveling with IBS-D to a 5-day conference in San Diego: how do you manage food — what most people get wrong about this on a low-carb or ketogenic diet? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ Were any of you guys fans of Journey? How big were they — what the research actually says? ▸ I am on my second week of mounjaro (2.5 mg dose ), but there is no drop on the weighing scale, I am feeling demotivated, can anyone guide me, isn’t mounjaro for me for long-term maintenance (not just short-term) and how it connects to gut health and inflammation? ▸ Is it possible that low carb is the only way I can eat specifically for women over 40 if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Insulin Resistance — A condition where your cells stop responding to insulin, locking fat in storage; our protocol is designed to unlock thes… ▸ Is the idea of the kitchen timer to eventually get to the point where someone has an orgasm just from hearing the ding? Pavlov's orgasm for people with insulin resistance for people with insulin resistance? ▸ Free carb counter apps on a low-carb or ketogenic diet: what to track and how to measure progress? ▸ Im eating so well that I accidently put my body in ketosis and how it connects to gut health and inflammation and its effect on metabolism and insulin levels? ▸ Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's during the weight loss plateau phase? ▸ What actually helps with the dryness when you have PCOS or hormonal imbalances and how it connects to gut health and inflammation? 📖 Hashimoto’s Success — Achieving weight loss and reduced inflammation in thyroid patients by removing dietary triggers like lectins and modern … ▸ Best Curcumin Supplements: how to talk to your doctor about this if you're on a GLP-1 like semaglutide or tirzepatide? ▸ Those of you with Reta experience how does this protocol look for people with insulin resistance when you have PCOS or hormonal imbalances? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 ▸ How I Lost 22lbs in 3 Months (155→133lbs at 5'8") after not being able to lose weight for a long time if you're on a GLP-1 like semaglutide or tirzepatide during the weight loss plateau phase? ▸ Got diagnosed today, where do i go from here — what do certified weight loss coaches recommend: best practices and common mistakes to avoid? 📖 Metabolic Reset — The process of retraining your body to utilize stored fat for fuel and regulating hunger hormones so you can maintain yo… ▸ Can autophagy regenerate muscle during physically active prolonged fast and how it connects to gut health and inflammation and its effect on metabolism and insulin levels? ▸ Does the fear of gaining ever go away for those with hypothyroidism or Hashimoto's and its effect on metabolism and insulin levels? ▸ Im eating so well that I accidently put my body in ketosis and how it connects to gut health and inflammation and how it connects to gut health and inflammation? ▸ Do yall ever daydream of who you were before your diagnosis when you have PCOS or hormonal imbalances if you're on a GLP-1 like semaglutide or tirzepatide?