Expert Q&A

Anyone seen anything like this? Painful spasms in my intestines for the past 5 months. What should I do?

Understanding Persistent Intestinal Spasms

If you've been dealing with painful spasms in your intestines for five months, you're not alone—especially if you're in your late 40s or early 50s managing hormonal changes, diabetes, and extra weight. These spasms often signal irritable bowel syndrome (IBS), small intestinal bacterial overgrowth (SIBO), or chronic inflammation tied to visceral fat. In my book, The CFP Gut Reset Protocol, I explain how excess abdominal fat triggers cytokine release that irritates the enteric nervous system, causing cramping, bloating, and irregular bowel habits that derail every diet you've tried.

Why This Hits Harder With Your Health Profile

At CFP Weight Loss, we see this pattern constantly: hormonal shifts in perimenopause slow gut motility by up to 30%, while high blood sugar from diabetes damages the vagus nerve, worsening spasms. Joint pain limits movement, creating a cycle where stress hormones like cortisol promote more belly fat and inflammation. Insurance rarely covers specialized testing, so most people suffer silently, embarrassed to discuss obesity-related digestive distress. The conflicting nutrition advice online only adds overwhelm—no wonder previous diets failed when your gut can't even process food properly.

Immediate Steps You Can Take Today

Start with a 7-day low-FODMAP trial: eliminate garlic, onions, wheat, and artificial sweeteners while increasing soluble fiber from oats and psyllium (aim for 25g daily). Track symptoms in a simple journal noting meals, stress, and pain levels on a 1-10 scale. For joint-friendly movement, try 10-minute chair marches or gentle yoga flows that won't aggravate your back or knees. Sip peppermint or ginger tea after meals—studies show they relax intestinal smooth muscle within 20 minutes. If spasms occur after eating, consider a digestive enzyme with meals containing 500mg betaine HCl to support stomach acid often low in those over 45.

When to Seek Professional Help and Long-Term Strategy

See your primary doctor promptly for bloodwork checking CRP, HbA1c, and thyroid levels, plus a referral for colonoscopy or breath testing if symptoms include unintended weight loss or blood in stool. At CFP Weight Loss, our 12-week program integrates gut healing with sustainable fat loss: we target 1-2 pounds weekly through anti-inflammatory Mediterranean-style meals requiring just 20 minutes prep. Many clients reduce spasms by 70% within six weeks while dropping 15-25 pounds, improving blood pressure and blood sugar without complex plans. The key is addressing root causes—hormones, inflammation, and microbiome—rather than another restrictive diet. You're not failing; your body is signaling for a smarter approach. Start small today, and consider joining our community for beginner-friendly guidance tailored to middle-income budgets and real-life schedules.

💬 What the Community Says

The community shows a mix of empathy and shared frustration with ongoing intestinal spasms lasting months. Many in the 45-55 age group report similar symptoms alongside stubborn weight, hormonal shifts, and diabetes management, often feeling dismissed by doctors who suggest stress or "just lose weight." A common theme is trying low-FODMAP, peppermint oil, or probiotics with mixed results—some see 50% pain reduction in 4-6 weeks, others struggle with insurance barriers to testing. Debates rage over whether it's IBS, SIBO, or food sensitivities, with a vocal minority warning against self-diagnosis while praising gentle movement like walking or yoga that doesn't flare joint pain. Lived experiences highlight embarrassment discussing gut issues with obesity, yet most find relief sharing meal ideas that fit busy schedules and don't break the bank. Overall sentiment leans toward cautious hope that combining medical checks with simple dietary resets can break the cycle after years of failed diets.
Clark, R. (2026). Anyone seen anything like this? Painful spasms in my intestines for the past 5 m. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/anyone-seen-anything-like-this-painful-spasms-in-my-intestines-for-the-past-5-months-what-should-i-do
Russell Clark, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Have a follow-up question?
More Questions 200 answered
Are Seed Oils Inflammatory if you're on a GLP-1 like semaglutide or tirzepatide How do you know you are in meno if you take continuous bc — how a functional medicine approach differs How does smoking affect GERD while taking tirzepatide? Has anyone switched from brand name Premarin to the new recently released generic conjugated estrogens and feels like it is not working as well while doing intermittent fasting How often can I eat in season fruits — how a functional medicine approach differs 📖 GLP-1 Receptor Agonist — A class of medication that mimics natural hormones to improve insulin secretion and slow gastric emptying, used strategi… Is Dotti a generic or brand-name patch and its effect on metabolism and insulin levels Has anyone been diagnosed with Hashimotos after going through emotional distress or chronic stress in general for those with hypothyroidism or Hashimoto's Zone 2 running is absurdly slow (slower than walking) — am I doing this right and the role of cortisol and stress hormones How to BOOST metabolism and BURN fat-- VERY EASY AND QUICK — how a functional medicine approach differs 📖 Diabetes Reversal — The clinical goal of restoring normal blood sugar levels and insulin function, as seen in patients like John who no long… When the clock starts over for those with hypothyroidism or Hashimoto's 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Is it just me or is Hashimoto’s greatly underrepresented while doing intermittent fasting Did exercise ever get rid of fatigue from insulin resistance while doing intermittent fasting Does the estradiol gel-associated bloating subside? 📖 The Clark Protocol — Our evidence-based framework that combines clinical nurse practitioner expertise with personal experience to solve the o… Anyone Here Successfully Reversed Insulin Resistance? What Actually Worked when you have PCOS or hormonal imbalances Anyone stretching out to 3 weeks between shots for people with insulin resistance Has anyone used Willow for people with insulin resistance 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… 2.5 mg no longer working. Move to 3.5 for people with insulin resistance How do you gauge progress from zone 2 while doing intermittent fasting 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Does anyone else love masks mandated so I can hide my facial hair while doing intermittent fasting Insulin resistance caused my weight gain despite eating low calorie diet, anyone else and the role of cortisol and stress hormones Post menopausal bleeding — how a functional medicine approach differs Guys, did you know the POWER of exercise for your body and its effect on metabolism and insulin levels Would doing this 2-3x a week help increase my Vo2 max specifically for women over 40 📖 Autophagy — The body's natural 'housecleaning' process that occurs during fasting or low-insulin states, promoted during our mainten… When the clock starts over while doing intermittent fasting Can I get an upvote for the true enemy of diabetes while doing intermittent fasting Has anyone switched from brand name Premarin to the new recently released generic conjugated estrogens and feels like it is not working as well for people with insulin resistance 📖 Metabolic Efficiency — The state where your body processes fuel cleanly and maintains high energy levels without the need for constant snacking… Has anyone switched from wegovy to mounjaro while doing intermittent fasting What is the Role of Metabolism in Immune System — how a functional medicine approach differs 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Has anyone used Willow while doing intermittent fasting 📖 Metabolic Stall — A plateau in weight loss often caused by hidden inflammation or hormonal adaptation, which we break using our specific 7… What keto plus compounded tirzepatide for the last five months looked like and how it connects to gut health and inflammation So if you're spacing out your shots - what are y'all doing with extra injectors and the role of cortisol and stress hormones Can deep extended autophagy reverse deep cavities, does anyone have any experience regarding this on a low-carb or ketogenic diet Two week pause, ok to return to current dose and the role of cortisol and stress hormones Eyelid myokymia/twitching caused by oral progesterone while doing intermittent fasting 📖 Tirzepatide Micro-Dosing — The practice of using the lowest effective dose to achieve results, minimizing side effects while maximizing the longevi… Two week pause, ok to return to current dose — how a functional medicine approach differs What is your best way to shift focus when starting and changing your HRT while doing intermittent fasting How I'm greeted most mornings — evidence-based answer for CFP patients 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Have to stop for 3 weeks for surgery and its effect on metabolism and insulin levels Has Gundry ever explained why he thinks APOE4 carriers love cheese so much while doing intermittent fasting Cool, happy energy after upping estrogen patch — how a functional medicine approach differs 📖 One Box Protocol — A revolutionary approach where we stretch one 60 mg box of tirzepatide across three metabolic phases, prioritizing long-… Insulin Resistance foods for poor people — evidence-based answer for CFP patients What keto plus compounded tirzepatide for the last five months looked like: best practices and common mistakes to avoid How long did it take you to lose weight on the Plant Paradox' for people with insulin resistance Anyone worried about the FDA crackdown and its effect on metabolism and insulin levels 📖 Rebound Weight Gain — The common 'yo-yo' effect caused by high-dose, continuous GLP-1 use; we prevent this through strategic cycling and metab… When feeling down, remember that PCOS is what helped our ancestors survive and the role of cortisol and stress hormones 📗 The 30-Week Tirzepatide Reset — Get Russell's complete protocol → Anyone in Maintenance w/ 15mg and the role of cortisol and stress hormones What would be the cause of insulin resistance: best practices and common mistakes to avoid Flexibility in the meal plan while doing intermittent fasting I'hv just stumbled upon autophagy and felt some hope for my situation. Is it really good for loose skin ? What can I do on a low-carb or ketogenic diet 📖 Ketogenic Foundation — Using low-carbohydrate principles to keep insulin low, allowing the tirzepatide to work more effectively at lower doses. When I smoke a little weed as a T1D and start feeling tingly and its effect on metabolism and insulin levels