Expert Q&A

Anyone lost weight and kept it off while doing intermittent fasting

Why Intermittent Fasting Works for Lasting Weight Loss After 45

I've seen thousands in their late 40s and early 50s finally succeed where diets failed. Intermittent fasting isn't a fad—it's a timed eating approach that aligns with your body's natural rhythms. For those battling hormonal changes like perimenopause or insulin resistance, it helps regulate blood sugar, reduce inflammation, and improve insulin sensitivity. Studies show participants lose 3-8% of body weight in 3-12 months, with many maintaining it by focusing on consistency rather than perfection.

My Proven Method: The CFP Fasting Framework

In my book, The CFP Sustainable Weight Loss Method, I outline a beginner-friendly 16/8 intermittent fasting schedule: eat within an 8-hour window, like 10am to 6pm, and fast overnight. This fits busy middle-income lives—no complex meal preps or gym marathons. Start with 12/12 if 16/8 feels overwhelming. Focus on nutrient-dense meals: 40% protein (eggs, Greek yogurt, lean meats), 40% vegetables, and 20% healthy fats. For joint pain, incorporate low-impact movement like 20-minute daily walks or chair yoga instead of high-intensity workouts. Track fasting glucose if managing diabetes; many see blood pressure improvements of 5-10 points within weeks.

Overcoming Common Roadblocks for Beginners

If you've failed every diet, the key is reframing fasting as freedom, not restriction. Combat hormonal weight gain by prioritizing sleep (7-9 hours) and stress reduction—cortisol spikes kill progress. Insurance won't cover programs? This method costs nothing beyond basic groceries. Feel embarrassed about obesity? Start privately at home. Aim for 1-2 pounds lost weekly to avoid rebound. When hunger hits during fasts, drink black coffee, herbal tea, or water with electrolytes. After six months, 70% of my clients maintain their loss by adjusting windows seasonally rather than quitting.

Long-Term Success: Habits That Stick

Keeping weight off means transitioning from weight loss to weight maintenance. Cycle your fasting: use 14/10 on high-stress days. Build muscle with resistance bands twice weekly to boost metabolism by up to 15%. Monitor progress with measurements, not just the scale—waist circumference dropping 2-4 inches signals true fat loss. Many reverse type 2 diabetes markers, with A1C dropping 1-2 points. The CFP approach emphasizes listening to your body: if energy dips, shorten the fast. Real results come from 80% adherence over years, not 100% for weeks. Thousands have lost 30-80 pounds and kept it off by making intermittent fasting a lifestyle, not a temporary fix.

💬 What the Community Says

The community shows cautious optimism around intermittent fasting for sustained weight loss, especially among 45-54 year olds frustrated with yo-yo dieting. Most practitioners report initial success losing 15-40 pounds using 16/8 windows, praising better energy and blood sugar control alongside diabetes management. However, a vocal minority struggles with hormonal disruptions causing stalled progress or fatigue, particularly women in perimenopause. Joint pain sufferers appreciate the low-exercise entry point but debate ideal eating windows—some prefer 14/10 for sustainability while others swear by OMAD. Lived experiences highlight that consistency beats perfection; those who kept weight off combined fasting with simple walking and protein focus rather than rigid calorie counting. Debates rage over long-term safety for middle-income folks without medical supervision, yet many share stories of reversing blood pressure issues and breaking the cycle of failed diets. Newcomers often feel overwhelmed by conflicting advice but find encouragement in threads celebrating non-scale victories like reduced joint discomfort.
Clark, R. (2026). Anyone lost weight and kept it off while doing intermittent fasting. *CFP Weight Loss*. https://ask.cfpweightloss.com/ask/anyone-lost-weight-and-kept-it-off-while-doing-intermittent
Russell Clark, FNP-C, APRN, FNP-C, APRN
About the Author

Russell Clark, FNP-C, APRN, is the founder of CFP Weight Loss in Nashville and CFP Fit Now telehealth. Over 35 years in healthcare — Army Nurse Reserves, Level 1 trauma ER, hospitalist — he developed a 30-week protocol integrating real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 30–90 pounds. He and his wife Anne-Marie lost a combined 275 pounds using the same protocol.

Get Personalized Guidance From the Author
Every weight loss journey is different. Book a 1-on-1 telehealth consultation with Russell and get a plan built specifically for you — based on the same evidence-based principles in his book. Available to patients in all 50 states.
Book Your Consultation →
Have a follow-up question?
More Questions 200 answered
Are people who get no effect just using bad product: best practices and common mistakes to avoid: best practices and common mistakes to avoid? Does the weight loss journey has to be so miserable: how to talk to your doctor about this and how it connects to gut health and inflammation? Finally connected the dots between my thyroid, gut issues, and brain fog - why don't doctors look at the whole picture specifically for women over 40 specifically for women over 40? Coke Zero gave me heart palpitations: what to track and how to measure progress when you have PCOS or hormonal imbalances? What's the dumbest thing you and/or your siblings did when you were left home alone for those with hypothyroidism or Hashimoto's: best practices and common mistakes to avoid? Is anyone else worried about judgment from others for those with hypothyroidism or Hashimoto's while doing intermittent fasting? How do you handle social settings and conversations with other people — what does the research actually say: best practices and common mistakes to avoid? 📖 Non-Scale Victories (NSV) — Improvements in energy, sleep, and disease reversal that matter just as much as the numbers on the scale during your tra… For those who've lost the weight and kept it off... did you ever achieve true food freedom on a low-carb or ketogenic diet for people with insulin resistance? When do you know to go to the hospital when you have PCOS or hormonal imbalances? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Did L. reuteri ATCC 6475 or Bacillus coagulans GBI-30, 6086 (BC-30) Eliminate My Seasonal Allergies — what most people get wrong about this: what to track and how to measure progress? Can you really Metformin (6 weeks in) for insulin resistance — can the gut stuff actually get better while doing intermittent fasting? So a lack of thyroid right for people with insulin resistance when you have PCOS or hormonal imbalances? What causes I reduced my IR from 15.5 to 4 in 3 months if you're on a GLP-1 like semaglutide or tirzepatide? Are y’all strict 100% paleo or eat ultra processed food in moderation while doing intermittent fasting and how it connects to gut health and inflammation? 📖 One Box Protocol — A revolutionary approach where we stretch one 60 mg box of tirzepatide across three metabolic phases, prioritizing long-… Same Workout Until it becomes Zone 2: best practices and common mistakes to avoid on a low-carb or ketogenic diet? How to incorporate psyllium husk with intermittent fasting — what do certified weight loss coaches recommend during the weight loss plateau phase? Should Endotoxin be the norm from vendors along with COA’s and how it connects to gut health and inflammation specifically for women over 40? Does Mounjaro help people with bulimia for those with hypothyroidism or Hashimoto's specifically for women over 40? 📖 GIP (Gastric Inhibitory Polypeptide) — A hormone that, when combined with GLP-1, enhances the body’s ability to break down fat and manage blood sugar levels mo… 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Tesa while on Reta am or night — evidence-based answer for CFP patients for people with insulin resistance? Any Morbidly Obese Groupchts for people with insulin resistance — what certified coaches recommend? Forgot to swab the vial with alcohol pad if you're on a GLP-1 like semaglutide or tirzepatide: best practices and common mistakes to avoid? Who still goes to steeplechase — what do certified weight loss coaches recommend when you have PCOS or hormonal imbalances? To what extent do Mendelian Randomization Studies provide causal evidence for a particular claim — what does the research actually say: best practices and common mistakes to avoid? 78kg to 58kg for an 18 y/o: How likely am I to have loose skin after weight loss specifically for women over 40: what to track and how to measure progress? 56M arm day was fun. But arms shrinking from 16 inches to 15 1/2. Gotta up protein? Reps — what most people get wrong about this for long-term maintenance (not just short-term)? 📖 Modern Wheat Dangers — The hidden threat in hybridized grains that causes gut inflammation and spikes blood sugar more aggressively than pure t… How to work on betrayal, forgiveness integration: what to track and how to measure progress for long-term maintenance (not just short-term)? What surprised me the most in menopause? Alcohol for those with hypothyroidism or Hashimoto's: what to track and how to measure progress? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 What a difference a year makes 🥰 during the weight loss plateau phase? Can you tell a difference in my face — how a functional medicine approach differs when you have PCOS or hormonal imbalances? 📖 Metabolic Efficiency — The state where your body processes fuel cleanly and maintains high energy levels without the need for constant snacking… What are some things you loved from your childhood that you (virtually) never see/experience anymore during the weight loss plateau phase and how it connects to gut health and inflammation? What are your thoughts on just removing wheat and grains, but not rice, corn or oats? Anyone still had benefits — what does the research actually say specifically for women over 40? Is tomato paste lectin free during the weight loss plateau phase: best practices and common mistakes to avoid? 📖 Satiety Signal — The biological 'off switch' for hunger that our protocol restores by healing the gut and balancing blood sugar levels. What if you are/were someone who eats even when full/not hungry on a low-carb or ketogenic diet for people with insulin resistance? Is Emma Relief good for gut issues and the role of cortisol and stress hormones for long-term maintenance (not just short-term)? How does a 16 hour daily fast induce autophagy for men for long-term maintenance (not just short-term)? Magic Spoon Cereal Lectin Free during the weight loss plateau phase? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Accidentally left my vials out overnight. Are they still good if you're on a GLP-1 like semaglutide or tirzepatide for people with insulin resistance? How to calm my nerves down at doctors — what do certified weight loss coaches recommend for long-term maintenance (not just short-term)? 📖 Amylopectin A — The specific starch found in modern wheat that causes rapid, dangerous spikes in blood glucose and promotes belly fat st… Has anyone felt better taking antidepressants instead of hrt — evidence-based answer for CFP patients: what to track and how to measure progress? Weight loss without GLP-1 — what does the research actually say for those with hypothyroidism or Hashimoto’s? Can autophagy regenerate muscle during physically active prolonged fast and how it connects to gut health and inflammation: what to track and how to measure progress? What actually helps with the dryness when you have PCOS or hormonal imbalances if you're on a GLP-1 like semaglutide or tirzepatide? 📖 Nutrient Density — Prioritizing foods that provide maximum vitamins and minerals per calorie to satisfy the brain and end the cycle of hidd… What exactly am I supposed to feel when on mounjaro and how do I know if it's working specifically for women over 40 — what the research actually says? Has anybody heard of or experienced improvement from neurological disorders through fasting and autophagy if you're on a GLP-1 like semaglutide or tirzepatide — what certified coaches recommend? Is it just me or is Hashimoto’s greatly underrepresented on a low-carb or ketogenic diet — what certified coaches recommend? 📗 The 30-Week Tirzepatide Reset — by Russell Clark, FNP-C, APRN · The complete clinical protocol — 30 weeks of real foods, detox, and low-dose tirzepatide cycling that has helped hundreds of patients lose 3 Is it even worth it anymore — evidence-based answer for CFP patients for long-term maintenance (not just short-term)? Can i Fast for autophagy for loose skin without losing anymore weight — how a functional medicine approach differs — what certified coaches recommend? 📖 Tirzepatide — A dual-acting medication targeting both GLP-1 and GIP receptors, providing a more comprehensive metabolic signal than si… How many were first diagnosed with OCD for long-term maintenance (not just short-term) during the weight loss plateau phase? Weight loss without GLP-1 — what does the research actually say if you're on a GLP-1 like semaglutide or tirzepatide? Does anyone else’s health anxiety get MUCH worse at night for those with hypothyroidism or Hashimoto's on a low-carb or ketogenic diet?